amyl nitrite indications/contra

Stem definitionDrug idCAS RN
NO2 - derivatives 205 8017-89-8

Description:

MoleculeDescription

Synonyms:

  • amyl nitrite
  • vaporole
  • nitramyl
  • amylnitrit
A vasodilator that is administered by inhalation. It is also used recreationally due to its supposed ability to induce euphoria and act as an aphrodisiac.
  • Molecular weight: 234.30
  • Formula: C10H22N2O4
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 38.66
  • ALOGS:
  • ROTB: None

Drug dosage:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC V03AB22 VARIOUS
ALL OTHER THERAPEUTIC PRODUCTS
ALL OTHER THERAPEUTIC PRODUCTS
Antidotes
CHEBI has role CHEBI:35620 vasodilator agent
CHEBI has role CHEBI:35674 antihypertensive agent
MeSH PA D002317 Cardiovascular Agents
MeSH PA D014665 Vasodilator Agents

Drug Use (View source of the data)

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DiseaseRelationSNOMED_IDDOID
Toxic effect of cyanide indication 66207005
Glaucoma contraindication 23986001 DOID:1686
Orthostatic hypotension contraindication 28651003
Methemoglobinemia contraindication 38959009 DOID:10783
Benign intracranial hypertension contraindication 68267002 DOID:11459
Injury of head contraindication 82271004
Anemia contraindication 271737000 DOID:2355
Cerebral hemorrhage contraindication 274100004
Angina pectoris off-label use 194828000

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
CHEBI:2691 CHEBI
4017514 VUID
N0000145899 NUI
C0002711 UMLSCUI
D00517 KEGG_DRUG
22T8Z09XAK UNII
4017514 VANDF
3836 MMSL
742 RXNORM
116655003 SNOMEDCT_US
387038004 SNOMEDCT_US
4197 MMSL
d00666 MMSL
N0000145899 NDFRT
N0000005927 NDFRT
000684 NDDF
DB01612 DRUGBANK_ID
CHEMBL3833339 ChEMBL_ID
D000680 MESH_DESCRIPTOR_UI
10026 PUBCHEM_CID

Pharmaceutical products:

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ProductCategoryIngredientsNDCFormQuantityRoute MarketingLabel
Amyl Nitrite HUMAN PRESCRIPTION DRUG LABEL 1 46414-2222 INHALANT 0.30 g RESPIRATORY (INHALATION) unapproved drug other 2 sections