oxolinic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibacterials, nalidixic acid derivatives 2024 14698-29-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • oxolinic acid
  • dioxacin
  • nidantin
  • prodoxal
Synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
  • Molecular weight: 261.23
  • Formula: C13H11NO5
  • CLOGP: 1.66
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 1
  • TPSA: 76.07
  • ALOGS: -2.14
  • ROTB: 2

Drug dosage:

DoseUnitRoute
1 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01MB05 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
QUINOLONE ANTIBACTERIALS
Other quinolones
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000892 Anti-Infective Agents, Urinary
MeSH PA D000970 Antineoplastic Agents
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D059005 Topoisomerase II Inhibitors
MeSH PA D059003 Topoisomerase Inhibitors
CHEBI has role CHEBI:23924 enzyme inhibitors
CHEBI has role CHEBI:33281 antibiotics
CHEBI has role CHEBI:35441 antiinfective agents
CHEBI has role CHEBI:35718 antifungal agents
CHEBI has role CHEBI:36047 antibacterial drugs

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.23 acidic
pKa2 2.58 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000166914 NUI
D02301 KEGG_DRUG
C0030031 UMLSCUI
CHEBI:138856 CHEBI
OXI PDB_CHEM_ID
CHEMBL416755 ChEMBL_ID
DB13627 DRUGBANK_ID
D010093 MESH_DESCRIPTOR_UI
4628 PUBCHEM_CID
1866 INN_ID
L0A22B22FT UNII
7798 RXNORM
002871 NDDF
66653008 SNOMEDCT_US

Pharmaceutical products:

None