oleandomycin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| antibiotics, produced by Streptomyces strains | 1983 | 3922-90-5 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Antibiotic macrolide produced by Streptomyces antibioticus.
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 1 | g | O |
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| Vd (Volume of distribution) | 0.77 L/kg | Lombardo F, Berellini G, Obach RS |
| CL (Clearance) | 9.10 mL/min/kg | Lombardo F, Berellini G, Obach RS |
| fu (Fraction unbound in plasma) | 0.40 % | Lombardo F, Berellini G, Obach RS |
| t_half (Half-life) | 1.05 hours | Lombardo F, Berellini G, Obach RS |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | J01FA05 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS Macrolides |
| ATC | J01RA08 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE COMBINATIONS OF ANTIBACTERIALS Combinations of antibacterials |
| MeSH PA | D000900 | Anti-Bacterial Agents |
| MeSH PA | D000890 | Anti-Infective Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Pneumococcal pneumonia | indication | 233607000 | |
| Upper Respiratory Streptococcal Infection | indication | ||
| Asthma | off-label use | 195967001 | DOID:2841 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 8.65 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| N0000007496 | NUI |
| 7060-74-4 | SECONDARY_CAS_RN |
| C0028923 | UMLSCUI |
| CHEBI:16869 | CHEBI |
| ZIO | PDB_CHEM_ID |
| CHEMBL606258 | ChEMBL_ID |
| CHEMBL2105788 | ChEMBL_ID |
| D009827 | MESH_DESCRIPTOR_UI |
| DB11442 | DRUGBANK_ID |
| 665 | INN_ID |
| P8ZQ646136 | UNII |
| 72493 | PUBCHEM_CID |
| 7629 | RXNORM |
| 002764 | NDDF |
| 006766 | NDDF |
| 41332001 | SNOMEDCT_US |
Pharmaceutical products:
None