norethindrone enanthate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
1964 3836-23-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • norethindrone enanthate
  • norethisterone enanthate
  • norethisterone heptanoate
  • norigest
  • noristerat
  • Molecular weight: 410.60
  • Formula: C27H38O3
  • CLOGP: 6.57
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 0
  • TPSA: 43.37
  • ALOGS: -5.44
  • ROTB: 7
  • Status: OFP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

PropertyValueReference
S (Water solubility) 0.01 mg/mL Bocci G, Oprea TI, Benet LZ

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AXL,BRAF,BTK,CAMK2D,CDK5,CDK9,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,ITK,MAP2K6,MAPK10,MAPK7,MAPKAPK2,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CG,PIM2,PRKDC,STK33,SYK,TEK,TGFBR1,ZAP70 31
kinase-selectivity-class EIF2AK3,GRK2 2
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
FDA CS M0447349 Progesterone Congeners
FDA Chemical/Ingredient N0000011301 Progesterone Congeners
MeSH PA D000080066 Contraceptive Agents, Hormonal
MeSH PA D003270 Contraceptive Agents
MeSH PA D003271 Contraceptive Agents, Female
MeSH PA D003280 Contraceptives, Oral, Synthetic
MeSH PA D012102 Reproductive Control Agents
MeSH PA D003278 Contraceptives, Oral, Hormonal
FDA EPC N0000175602 Progestin
CHEBI has role CHEBI:49326 synthetic oral contraceptives
CHEBI has role CHEBI:59826 progestins

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4018496 VANDF
C0068981 UMLSCUI
CHEBI:34894 CHEBI
DB14678 DRUGBANK_ID
C024319 MESH_SUPPLEMENTAL_RECORD_UI
229295 PUBCHEM_CID
HY3S2K0J0F UNII
31984 RXNORM
182290 MMSL
5187 MMSL
d00555 MMSL
001298 NDDF
001326 NDDF
005653 NDDF
126102009 SNOMEDCT_US
395811006 SNOMEDCT_US
63758001 SNOMEDCT_US
C0028356 UMLSCUI
DB00717 DRUGBANK_ID
6230 PUBCHEM_CID
687 INN_ID
D009640 MESH_DESCRIPTOR_UI
CHEBI:7627 CHEBI
HY3S2K0J0F INXIGHT DRUGS

Pharmaceutical products:

None