nifenazone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
anti-inflammatory analgesics, phenylbutazone derivatives 1924 2139-47-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • nifenazone dihydrochloride
  • nikofezon
  • nifenazone
  • nicophesone
  • niapyrin
  • nicazane
  • nicodone
  • nicofesone
  • nicophezon
  • nicotazone
  • nifenazon
  • phenicazone
  • niprazine
  • Molecular weight: 308.34
  • Formula: C17H16N4O2
  • CLOGP: 0.12
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 1
  • TPSA: 65.54
  • ALOGS: -2.91
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC M02AA24 MUSCULO-SKELETAL SYSTEM
TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
Antiinflammatory preparations, non-steroids for topical use
ATC N02BB05 NERVOUS SYSTEM
ANALGESICS
OTHER ANALGESICS AND ANTIPYRETICS
Pyrazolones
MeSH PA D000700 Analgesics
MeSH PA D018712 Analgesics, Non-Narcotic
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000894 Anti-Inflammatory Agents, Non-Steroidal
MeSH PA D018501 Antirheumatic Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.29 acidic
pKa2 4.01 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01437 KEGG_DRUG
51658-08-3 SECONDARY_CAS_RN
C0068738 UMLSCUI
CHEBI:31910 CHEBI
CHEMBL1413176 ChEMBL_ID
DB13407 DRUGBANK_ID
C005249 MESH_SUPPLEMENTAL_RECORD_UI
4487 PUBCHEM_CID
1834 INN_ID
8780F0K71U UNII

Pharmaceutical products:

None