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2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
Download
L1000
FAQ
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
nialamide 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
1907
51-12-7
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
nialamide
nialamid
niamid
niamidal
niamide
niaquitil
niazin
An MAO inhibitor that is used as an antidepressive agent.
Molecular weight: 298.35
Formula: C16H18N4O2
CLOGP: 0.91
LIPINSKI: 0
HAC: 6
HDO: 3
TPSA: 83.12
ALOGS: -3.53
ROTB: 7
Drug dosage:
Dose
Unit
Route
0.10
g
O
ADMET properties:
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Property
Value
Reference
S (Water solubility)
2.27 mg/mL
Bocci G, Oprea TI, Benet LZ
BDDCS (Biopharmaceutical Drug Disposition Classification System)
1
Hosey CM, Chan R, Benet LZ
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Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
N06AF02
NERVOUS SYSTEM
PSYCHOANALEPTICS
ANTIDEPRESSANTS
Monoamine oxidase inhibitors, non-selective
CHEBI has role
CHEBI:22586
antioxidants
CHEBI has role
CHEBI:23357
cofactor
CHEBI has role
CHEBI:25212
metabolites
CHEBI has role
CHEBI:61115
histone deacetylase inhibitors
CHEBI has role
CHEBI:62913
PARP
CHEBI has role
CHEBI:63726
neuroprotective agents
CHEBI has role
CHEBI:67079
anti-inflammatory agents
CHEBI has role
CHEBI:71181
Sir2 inhibitors
CHEBI has role
CHEBI:75771
Mus musculus metabolites
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
11.18
acidic
pKa2
12.9
acidic
pKa3
3.65
Basic
pKa4
0.0
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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entries
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ID
Source
001494
NDDF
4472
PUBCHEM_CID
49313009
SNOMEDCT_US
7394
RXNORM
899
INN_ID
C0027999
UMLSCUI
CHEBI:94510
CHEBI
CHEMBL1256841
ChEMBL_ID
D009526
MESH_DESCRIPTOR_UI
D07337
KEGG_DRUG
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Pharmaceutical products:
None
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nialamide