mydecamycin indications/contra

Stem definitionDrug idCAS RN
antibiotics, produced by Streptomyces strains 1861 35457-80-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • mydecamycin
  • aboren
  • Espinomycin A
  • Medecamycin A1
  • medemycin
  • Medemycin A1
  • midecamycin
  • Midecamycin A1
  • Platenomycin B1
  • rubimycin
  • turimycin
macrolide antibiotic from Streptomyces hygroscopicus JA 6599; structure
  • Molecular weight: 813.98
  • Formula: C41H67NO15
  • CLOGP: 3.27
  • LIPINSKI: 2
  • HAC: 16
  • HDO: 3
  • TPSA: 206.05
  • ALOGS: -3.94
  • ROTB: 14

Drug dosage:

DoseUnitRoute
1 g P

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC J01FA03 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
Macrolides
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.8 acidic
pKa2 13.95 acidic
pKa3 7.88 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
C0066531 UMLSCUI
D01339 KEGG_DRUG
30005 RXNORM
703378009 SNOMEDCT_US
703379001 SNOMEDCT_US
005381 NDDF
CHEMBL448615 ChEMBL_ID
C011138 MESH_SUPPLEMENTAL_RECORD_UI
CHEMBL1908336 ChEMBL_ID
5282169 PUBCHEM_CID
N34Z0Y5UH7 UNII
3461 INN_ID
C026483 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None