Stem definition | Drug id | CAS RN |
---|---|---|
prednisone and prednisolone derivatives | 1832 | 83919-23-7 |
Dose | Unit | Route |
---|---|---|
0.20 | mg | N |
0.40 | mg | Inhal.powder |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 0.50 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 0.02 µM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
Vd (Volume of distribution) | 2.20 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 12.70 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.01 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 4.40 hours | Lombardo F, Berellini G, Obach RS |
BA (Bioavailability) | 0.00 % | Kawashima H, Watanabe R, Esaki T, Kuroda M, Nagao C, Natsume-Kitatani Y, Ohashi R, Komura H, Mizuguchi K |
BA (Bioavailability) | 0.01 % | Kawashima H, Watanabe R, Esaki T, Kuroda M, Nagao C, Natsume-Kitatani Y, Ohashi R, Komura H, Mizuguchi K |
Date | Agency | Company | Orphan |
---|---|---|---|
April 30, 1987 | FDA | MERCK SHARP DOHME | |
June 29, 2020 | PMDA | Novartis Pharma K.K. | |
May 30, 2020 | EMA | Novartis Europharm Limited |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Product quality issue | 4905.95 | 11.49 | 1780 | 74525 | 34085 | 63378632 |
No adverse event | 2975.56 | 11.49 | 1292 | 75013 | 40113 | 63372604 |
Poor quality device used | 2499.22 | 11.49 | 564 | 75741 | 1507 | 63411210 |
Product dose omission issue | 1860.33 | 11.49 | 1813 | 74492 | 232500 | 63180217 |
Asthma | 716.31 | 11.49 | 823 | 75482 | 126738 | 63285979 |
Product container issue | 623.33 | 11.49 | 181 | 76124 | 1612 | 63411105 |
Gastrooesophageal reflux disease | 563.62 | 11.49 | 633 | 75672 | 95006 | 63317711 |
Device malfunction | 558.60 | 11.49 | 317 | 75988 | 17540 | 63395177 |
Wheezing | 511.52 | 11.49 | 602 | 75703 | 94993 | 63317724 |
Rhinitis allergic | 396.15 | 11.49 | 219 | 76086 | 11508 | 63401209 |
Circumstance or information capable of leading to medication error | 375.82 | 11.49 | 150 | 76155 | 3720 | 63408997 |
Ejection fraction | 326.34 | 11.49 | 119 | 76186 | 2287 | 63410430 |
Sleep disorder due to a general medical condition | 324.65 | 11.49 | 195 | 76110 | 11993 | 63400724 |
Sensitisation | 310.70 | 11.49 | 126 | 76179 | 3260 | 63409457 |
Sputum discoloured | 300.32 | 11.49 | 207 | 76098 | 16140 | 63396577 |
Polycystic ovaries | 292.85 | 11.49 | 131 | 76174 | 4340 | 63408377 |
Cough | 268.51 | 11.49 | 867 | 75438 | 291876 | 63120841 |
Sleep apnoea syndrome | 243.88 | 11.49 | 233 | 76072 | 28900 | 63383817 |
Blood test abnormal | 243.49 | 11.49 | 179 | 76126 | 15450 | 63397267 |
Nasal polyps | 232.45 | 11.49 | 123 | 76182 | 5916 | 63406801 |
Productive cough | 225.23 | 11.49 | 326 | 75979 | 62882 | 63349835 |
Dyspnoea | 203.22 | 11.49 | 1423 | 74882 | 659890 | 62752827 |
Synovitis | 197.23 | 11.49 | 6 | 76299 | 186912 | 63225805 |
Full blood count abnormal | 195.26 | 11.49 | 215 | 76090 | 31502 | 63381215 |
Glossodynia | 174.58 | 11.49 | 10 | 76295 | 178866 | 63233851 |
Obstructive airways disorder | 174.08 | 11.49 | 166 | 76139 | 20533 | 63392184 |
Contraindicated product administered | 173.63 | 11.49 | 27 | 76278 | 217621 | 63195096 |
Toxicity to various agents | 165.76 | 11.49 | 46 | 76259 | 247204 | 63165513 |
Hand deformity | 165.09 | 11.49 | 6 | 76299 | 159451 | 63253266 |
Systemic lupus erythematosus | 164.21 | 11.49 | 27 | 76278 | 208891 | 63203826 |
Pneumonia aspiration | 157.72 | 11.49 | 201 | 76104 | 34339 | 63378378 |
Incorrect dose administered | 154.98 | 11.49 | 267 | 76038 | 59701 | 63353016 |
Nasal congestion | 146.23 | 11.49 | 274 | 76031 | 65386 | 63347331 |
Bronchiectasis | 136.77 | 11.49 | 130 | 76175 | 16012 | 63396705 |
Presbyacusis | 135.34 | 11.49 | 67 | 76238 | 2798 | 63409919 |
Infective pulmonary exacerbation of cystic fibrosis | 135.11 | 11.49 | 100 | 76205 | 8717 | 63404000 |
Death | 132.49 | 11.49 | 153 | 76152 | 374228 | 63038489 |
Carpal tunnel syndrome | 131.39 | 11.49 | 143 | 76162 | 20674 | 63392043 |
Pericarditis | 129.47 | 11.49 | 7 | 76298 | 131572 | 63281145 |
Steroid withdrawal syndrome | 129.27 | 11.49 | 41 | 76264 | 504 | 63412213 |
Pleural fibrosis | 128.78 | 11.49 | 69 | 76236 | 3403 | 63409314 |
Asthma-chronic obstructive pulmonary disease overlap syndrome | 127.39 | 11.49 | 58 | 76247 | 2003 | 63410714 |
Wound | 126.28 | 11.49 | 22 | 76283 | 163241 | 63249476 |
Pleural thickening | 120.32 | 11.49 | 62 | 76243 | 2821 | 63409896 |
Burning sensation | 114.90 | 11.49 | 222 | 76083 | 54185 | 63358532 |
Chest discomfort | 113.71 | 11.49 | 340 | 75965 | 109629 | 63303088 |
Deafness neurosensory | 112.28 | 11.49 | 71 | 76234 | 4784 | 63407933 |
Total lung capacity increased | 112.04 | 11.49 | 55 | 76250 | 2255 | 63410462 |
Blood magnesium increased | 111.63 | 11.49 | 60 | 76245 | 2978 | 63409739 |
Bronchopulmonary aspergillosis allergic | 110.23 | 11.49 | 54 | 76251 | 2204 | 63410513 |
Maternal exposure during pregnancy | 109.94 | 11.49 | 64 | 76241 | 219998 | 63192719 |
Alopecia | 107.87 | 11.49 | 149 | 76156 | 337387 | 63075330 |
Abdominal discomfort | 104.19 | 11.49 | 140 | 76165 | 320745 | 63091972 |
Ejection fraction abnormal | 103.34 | 11.49 | 48 | 76257 | 1737 | 63410980 |
Off label use | 101.45 | 11.49 | 442 | 75863 | 674020 | 62738697 |
Acute kidney injury | 99.36 | 11.49 | 102 | 76203 | 263313 | 63149404 |
Neutropenia | 97.68 | 11.49 | 44 | 76261 | 174961 | 63237756 |
Nephrectomy | 94.99 | 11.49 | 43 | 76262 | 1465 | 63411252 |
Sinusitis | 94.27 | 11.49 | 528 | 75777 | 226125 | 63186592 |
Joint swelling | 93.72 | 11.49 | 156 | 76149 | 327510 | 63085207 |
Underdose | 92.52 | 11.49 | 138 | 76167 | 27318 | 63385399 |
Helicobacter infection | 91.07 | 11.49 | 5 | 76300 | 92780 | 63319937 |
Rheumatoid factor positive | 87.95 | 11.49 | 3 | 76302 | 84403 | 63328314 |
Swelling | 87.50 | 11.49 | 122 | 76183 | 275256 | 63137461 |
Arthropathy | 87.31 | 11.49 | 92 | 76213 | 234700 | 63178017 |
Therapeutic product effect incomplete | 86.45 | 11.49 | 338 | 75967 | 124718 | 63287999 |
Epigastric discomfort | 84.45 | 11.49 | 68 | 76237 | 6712 | 63406005 |
Rales | 81.48 | 11.49 | 88 | 76217 | 12609 | 63400108 |
Sinus disorder | 80.72 | 11.49 | 122 | 76183 | 24431 | 63388286 |
Infusion related reaction | 79.77 | 11.49 | 107 | 76198 | 245414 | 63167303 |
Cardiac disorder | 77.90 | 11.49 | 182 | 76123 | 50634 | 63362083 |
Cyst | 75.60 | 11.49 | 89 | 76216 | 14010 | 63398707 |
Hypothyroidism | 74.65 | 11.49 | 161 | 76144 | 42471 | 63370246 |
Thrombocytopenia | 73.99 | 11.49 | 45 | 76260 | 151112 | 63261605 |
General physical health deterioration | 72.56 | 11.49 | 81 | 76224 | 201321 | 63211396 |
Asthma exercise induced | 71.62 | 11.49 | 23 | 76282 | 295 | 63412422 |
Sarcoidosis | 71.33 | 11.49 | 63 | 76242 | 7059 | 63405658 |
Drug abuse | 70.88 | 11.49 | 4 | 76301 | 72514 | 63340203 |
Lung opacity | 69.96 | 11.49 | 45 | 76260 | 3123 | 63409594 |
Intentional overdose | 69.76 | 11.49 | 5 | 76300 | 74147 | 63338570 |
Product taste abnormal | 68.14 | 11.49 | 38 | 76267 | 2029 | 63410688 |
Coma | 67.43 | 11.49 | 200 | 76105 | 64164 | 63348553 |
Rhinitis | 66.41 | 11.49 | 75 | 76230 | 11291 | 63401426 |
Factor V Leiden mutation | 65.82 | 11.49 | 20 | 76285 | 211 | 63412506 |
Bone cyst | 65.08 | 11.49 | 38 | 76267 | 2216 | 63410501 |
Renal disorder | 64.12 | 11.49 | 130 | 76175 | 32844 | 63379873 |
Osteopenia | 61.79 | 11.49 | 96 | 76209 | 19689 | 63393028 |
Discomfort | 60.62 | 11.49 | 67 | 76238 | 167307 | 63245410 |
Vomiting | 60.60 | 11.49 | 409 | 75896 | 559208 | 62853509 |
Confusional state | 60.00 | 11.49 | 121 | 76184 | 236259 | 63176458 |
Nasal discomfort | 59.83 | 11.49 | 48 | 76257 | 4712 | 63408005 |
Dysphonia | 59.76 | 11.49 | 158 | 76147 | 47456 | 63365261 |
Anosmia | 59.54 | 11.49 | 56 | 76249 | 6804 | 63405913 |
Headache | 57.98 | 11.49 | 1075 | 75230 | 632166 | 62780551 |
Therapeutic product effect decreased | 57.02 | 11.49 | 90 | 76215 | 193097 | 63219620 |
Overdose | 56.67 | 11.49 | 34 | 76271 | 115044 | 63297673 |
Anaemia | 56.66 | 11.49 | 173 | 76132 | 293257 | 63119460 |
Drug interaction | 55.86 | 11.49 | 120 | 76185 | 229011 | 63183706 |
Folliculitis | 55.39 | 11.49 | 9 | 76296 | 70308 | 63342409 |
Impaired healing | 55.31 | 11.49 | 27 | 76278 | 102515 | 63310202 |
Rhinorrhoea | 55.20 | 11.49 | 189 | 76116 | 65388 | 63347329 |
Upper-airway cough syndrome | 54.57 | 11.49 | 68 | 76237 | 11350 | 63401367 |
Bronchitis | 54.51 | 11.49 | 295 | 76010 | 124640 | 63288077 |
Loss of personal independence in daily activities | 54.00 | 11.49 | 246 | 76059 | 97044 | 63315673 |
Wrong technique in device usage process | 53.32 | 11.49 | 40 | 76265 | 3558 | 63409159 |
Prolonged expiration | 52.87 | 11.49 | 26 | 76279 | 1070 | 63411647 |
Heart sounds | 52.18 | 11.49 | 25 | 76280 | 971 | 63411746 |
Urinary tract discomfort | 51.90 | 11.49 | 22 | 76283 | 638 | 63412079 |
Total lung capacity decreased | 50.67 | 11.49 | 32 | 76273 | 2151 | 63410566 |
Leukopenia | 50.58 | 11.49 | 15 | 76290 | 77275 | 63335442 |
Middle insomnia | 49.11 | 11.49 | 68 | 76237 | 12575 | 63400142 |
Poor quality product administered | 48.81 | 11.49 | 36 | 76269 | 3120 | 63409597 |
Pancytopenia | 48.63 | 11.49 | 28 | 76277 | 96905 | 63315812 |
Hypotension | 48.26 | 11.49 | 167 | 76138 | 272437 | 63140280 |
Dermatitis atopic | 48.23 | 11.49 | 59 | 76246 | 9665 | 63403052 |
Chronic obstructive pulmonary disease | 47.05 | 11.49 | 174 | 76131 | 62512 | 63350205 |
Sinus pain | 46.33 | 11.49 | 36 | 76269 | 3374 | 63409343 |
Osteosclerosis | 46.32 | 11.49 | 38 | 76267 | 3850 | 63408867 |
Occupational asthma | 46.22 | 11.49 | 14 | 76291 | 146 | 63412571 |
Dry eye | 45.90 | 11.49 | 130 | 76175 | 40631 | 63372086 |
Alveolar osteitis | 45.34 | 11.49 | 22 | 76283 | 879 | 63411838 |
Multiple organ dysfunction syndrome | 45.30 | 11.49 | 7 | 76298 | 56745 | 63355972 |
Oropharyngeal pain | 45.27 | 11.49 | 229 | 76076 | 94258 | 63318459 |
Bronchial obstruction | 45.08 | 11.49 | 26 | 76279 | 1481 | 63411236 |
Cardiac arrest | 44.65 | 11.49 | 28 | 76277 | 92517 | 63320200 |
Tunnel vision | 44.63 | 11.49 | 24 | 76281 | 1192 | 63411525 |
Irritable bowel syndrome | 43.99 | 11.49 | 22 | 76283 | 82390 | 63330327 |
Forced expiratory volume decreased | 43.97 | 11.49 | 41 | 76264 | 4927 | 63407790 |
Febrile neutropenia | 43.33 | 11.49 | 47 | 76258 | 118402 | 63294315 |
Cardiac murmur | 43.21 | 11.49 | 69 | 76236 | 14483 | 63398234 |
Diarrhoea | 42.94 | 11.49 | 604 | 75701 | 714762 | 62697955 |
Hepatic enzyme increased | 42.92 | 11.49 | 114 | 76191 | 202214 | 63210503 |
Pain | 41.78 | 11.49 | 633 | 75672 | 739995 | 62672722 |
Platelet count decreased | 41.47 | 11.49 | 47 | 76258 | 116075 | 63296642 |
Hyponatraemia | 41.38 | 11.49 | 44 | 76261 | 111856 | 63300861 |
Intentional product use issue | 41.23 | 11.49 | 56 | 76249 | 127836 | 63284881 |
Animal scratch | 41.19 | 11.49 | 24 | 76281 | 1394 | 63411323 |
Condition aggravated | 40.99 | 11.49 | 299 | 76006 | 401918 | 63010799 |
Liver injury | 40.98 | 11.49 | 11 | 76294 | 60509 | 63352208 |
Eosinophilic granulomatosis with polyangiitis | 40.82 | 11.49 | 28 | 76277 | 2164 | 63410553 |
Product odour abnormal | 40.48 | 11.49 | 23 | 76282 | 1273 | 63411444 |
Hyperkalaemia | 38.35 | 11.49 | 9 | 76296 | 54194 | 63358523 |
Disease progression | 37.34 | 11.49 | 56 | 76249 | 122702 | 63290015 |
Somnolence | 37.31 | 11.49 | 353 | 75952 | 178332 | 63234385 |
Metabolic acidosis | 37.27 | 11.49 | 5 | 76300 | 45064 | 63367653 |
Oesophageal dilatation | 37.05 | 11.49 | 15 | 76290 | 386 | 63412331 |
Asthenopia | 36.92 | 11.49 | 27 | 76278 | 2310 | 63410407 |
Dehydration | 36.51 | 11.49 | 98 | 76207 | 173256 | 63239461 |
Swelling face | 36.34 | 11.49 | 162 | 76143 | 63313 | 63349404 |
Sleep disorder | 35.83 | 11.49 | 193 | 76112 | 81373 | 63331344 |
C-reactive protein increased | 35.29 | 11.49 | 37 | 76268 | 94670 | 63318047 |
Respiration abnormal | 35.22 | 11.49 | 41 | 76264 | 6376 | 63406341 |
Therapy non-responder | 35.21 | 11.49 | 24 | 76281 | 75877 | 63336840 |
Ear congestion | 35.06 | 11.49 | 28 | 76277 | 2731 | 63409986 |
Mucosal inflammation | 34.81 | 11.49 | 7 | 76298 | 46921 | 63365796 |
Swollen tongue | 34.43 | 11.49 | 106 | 76199 | 34694 | 63378023 |
Respiratory tract congestion | 34.30 | 11.49 | 70 | 76235 | 17762 | 63394955 |
Exposure during pregnancy | 34.24 | 11.49 | 86 | 76219 | 155461 | 63257256 |
Drug intolerance | 33.61 | 11.49 | 225 | 76080 | 308436 | 63104281 |
Cardio-respiratory arrest | 33.54 | 11.49 | 15 | 76290 | 59944 | 63352773 |
Hip arthroplasty | 33.53 | 11.49 | 8 | 76297 | 47638 | 63365079 |
Neutrophil count decreased | 33.34 | 11.49 | 13 | 76292 | 56393 | 63356324 |
Eczema | 32.54 | 11.49 | 99 | 76206 | 32192 | 63380525 |
Palpitations | 32.18 | 11.49 | 239 | 76066 | 112531 | 63300186 |
Seasonal allergy | 32.06 | 11.49 | 75 | 76230 | 20875 | 63391842 |
Upper respiratory tract infection | 31.97 | 11.49 | 188 | 76117 | 81859 | 63330858 |
Nasal mucosal disorder | 31.54 | 11.49 | 14 | 76291 | 455 | 63412262 |
Expired product administered | 31.46 | 11.49 | 38 | 76267 | 6143 | 63406574 |
White blood cell count decreased | 31.32 | 11.49 | 76 | 76229 | 139028 | 63273689 |
Paranasal sinus discomfort | 31.05 | 11.49 | 32 | 76273 | 4344 | 63408373 |
Circumstance or information capable of leading to device use error | 31.02 | 11.49 | 10 | 76295 | 130 | 63412587 |
Incorrect dose administered by product | 30.98 | 11.49 | 11 | 76294 | 195 | 63412522 |
Bladder pain | 30.56 | 11.49 | 24 | 76281 | 2284 | 63410433 |
Drug ineffective | 30.56 | 11.49 | 991 | 75314 | 1043774 | 62368943 |
Decreased appetite | 30.42 | 11.49 | 177 | 76128 | 250875 | 63161842 |
Lactic acidosis | 29.93 | 11.49 | 5 | 76300 | 38282 | 63374435 |
Peripheral swelling | 29.88 | 11.49 | 192 | 76113 | 265750 | 63146967 |
Skin lesion | 29.86 | 11.49 | 93 | 76212 | 30628 | 63382089 |
Septic shock | 29.68 | 11.49 | 22 | 76283 | 66607 | 63346110 |
Knee arthroplasty | 29.64 | 11.49 | 14 | 76291 | 54192 | 63358525 |
Blood potassium increased | 29.62 | 11.49 | 67 | 76238 | 18242 | 63394475 |
Inappropriate schedule of product administration | 29.47 | 11.49 | 220 | 76085 | 103745 | 63308972 |
Hypomania | 29.14 | 11.49 | 37 | 76268 | 6293 | 63406424 |
Pre-existing condition improved | 28.58 | 11.49 | 42 | 76263 | 8202 | 63404515 |
Rheumatoid arthritis | 28.13 | 11.49 | 184 | 76121 | 253635 | 63159082 |
Skin weeping | 28.02 | 11.49 | 15 | 76290 | 738 | 63411979 |
Haemoptysis | 27.95 | 11.49 | 87 | 76218 | 28639 | 63384078 |
Female sterilisation | 27.92 | 11.49 | 14 | 76291 | 601 | 63412116 |
CFTR gene mutation | 27.92 | 11.49 | 9 | 76296 | 117 | 63412600 |
Sepsis | 27.61 | 11.49 | 93 | 76212 | 153030 | 63259687 |
Renal failure | 27.51 | 11.49 | 63 | 76242 | 117589 | 63295128 |
Product use issue | 26.97 | 11.49 | 155 | 76150 | 220365 | 63192352 |
Dyspnoea exertional | 26.69 | 11.49 | 143 | 76162 | 60159 | 63352558 |
Epistaxis | 26.65 | 11.49 | 164 | 76141 | 72561 | 63340156 |
Pulmonary function test decreased | 26.46 | 11.49 | 28 | 76277 | 3919 | 63408798 |
Red blood cell sedimentation rate increased | 26.22 | 11.49 | 10 | 76295 | 43972 | 63368745 |
Acquired haemophilia | 26.17 | 11.49 | 16 | 76289 | 1015 | 63411702 |
Suicide attempt | 26.01 | 11.49 | 21 | 76284 | 60897 | 63351820 |
Anxiety | 25.93 | 11.49 | 386 | 75919 | 217155 | 63195562 |
Lung perforation | 25.87 | 11.49 | 8 | 76297 | 90 | 63412627 |
Rash | 25.82 | 11.49 | 497 | 75808 | 560374 | 62852343 |
Cholelithiasis | 25.81 | 11.49 | 113 | 76192 | 43812 | 63368905 |
Interstitial lung disease | 25.62 | 11.49 | 22 | 76283 | 61886 | 63350831 |
Blister | 25.40 | 11.49 | 76 | 76229 | 129738 | 63282979 |
Throat irritation | 25.37 | 11.49 | 101 | 76204 | 37546 | 63375171 |
Adrenal suppression | 25.16 | 11.49 | 15 | 76290 | 909 | 63411808 |
Product quality control issue | 25.14 | 11.49 | 6 | 76299 | 22 | 63412695 |
Jaundice cholestatic | 24.94 | 11.49 | 37 | 76268 | 7287 | 63405430 |
Painful respiration | 24.76 | 11.49 | 23 | 76282 | 2751 | 63409966 |
Blood calcium increased | 24.62 | 11.49 | 42 | 76263 | 9308 | 63403409 |
Nasal disorder | 24.13 | 11.49 | 23 | 76282 | 2841 | 63409876 |
Glaucoma | 23.98 | 11.49 | 63 | 76242 | 18842 | 63393875 |
Treatment failure | 23.75 | 11.49 | 141 | 76164 | 198902 | 63213815 |
Product availability issue | 23.75 | 11.49 | 27 | 76278 | 4094 | 63408623 |
Electrocardiogram QT prolonged | 23.62 | 11.49 | 22 | 76283 | 59508 | 63353209 |
Respiratory tract infection | 23.08 | 11.49 | 105 | 76200 | 41378 | 63371339 |
Fibromyalgia | 22.68 | 11.49 | 170 | 76135 | 80250 | 63332467 |
Exposure to allergen | 22.67 | 11.49 | 10 | 76295 | 320 | 63412397 |
Encephalopathy | 22.66 | 11.49 | 9 | 76296 | 38611 | 63374106 |
Sinus congestion | 22.59 | 11.49 | 60 | 76245 | 18063 | 63394654 |
Pneumonia | 22.55 | 11.49 | 713 | 75592 | 456054 | 62956663 |
Delirium | 22.11 | 11.49 | 17 | 76288 | 50524 | 63362193 |
Ureteral disorder | 21.97 | 11.49 | 10 | 76295 | 345 | 63412372 |
Diaphragmatic rupture | 21.49 | 11.49 | 9 | 76296 | 253 | 63412464 |
Wound secretion | 21.29 | 11.49 | 27 | 76278 | 4587 | 63408130 |
Skin fragility | 20.96 | 11.49 | 12 | 76293 | 674 | 63412043 |
Malignant neoplasm progression | 20.84 | 11.49 | 42 | 76263 | 82079 | 63330638 |
Vital capacity decreased | 20.82 | 11.49 | 17 | 76288 | 1711 | 63411006 |
Croup infectious | 20.65 | 11.49 | 11 | 76294 | 536 | 63412181 |
Obstruction | 20.64 | 11.49 | 22 | 76283 | 3105 | 63409612 |
Hypophagia | 20.57 | 11.49 | 6 | 76299 | 31253 | 63381464 |
Depressive symptom | 20.52 | 11.49 | 25 | 76280 | 4077 | 63408640 |
Product dosage form issue | 20.22 | 11.49 | 5 | 76300 | 22 | 63412695 |
Aspiration | 20.17 | 11.49 | 42 | 76263 | 10809 | 63401908 |
Haemoglobin decreased | 20.15 | 11.49 | 98 | 76207 | 145387 | 63267330 |
Adiposis dolorosa | 19.95 | 11.49 | 9 | 76296 | 304 | 63412413 |
Fatigue | 19.94 | 11.49 | 869 | 75436 | 887159 | 62525558 |
Arthralgia | 19.91 | 11.49 | 527 | 75778 | 569183 | 62843534 |
Nasal dryness | 19.87 | 11.49 | 26 | 76279 | 4555 | 63408162 |
International normalised ratio increased | 19.82 | 11.49 | 16 | 76289 | 46409 | 63366308 |
Hepatic failure | 19.82 | 11.49 | 9 | 76296 | 35647 | 63377070 |
Gastrointestinal haemorrhage | 19.35 | 11.49 | 43 | 76262 | 81133 | 63331584 |
Enthesopathy | 19.22 | 11.49 | 36 | 76269 | 8578 | 63404139 |
Perfume sensitivity | 19.18 | 11.49 | 12 | 76293 | 793 | 63411924 |
Psoriatic arthropathy | 19.06 | 11.49 | 52 | 76253 | 91468 | 63321249 |
Fall | 18.85 | 11.49 | 345 | 75960 | 391989 | 63020728 |
Skin burning sensation | 18.84 | 11.49 | 45 | 76260 | 12689 | 63400028 |
Polymyalgia rheumatica | 18.80 | 11.49 | 23 | 76282 | 3768 | 63408949 |
Lung neoplasm malignant | 18.68 | 11.49 | 59 | 76246 | 19574 | 63393143 |
Sneezing | 18.49 | 11.49 | 56 | 76249 | 18162 | 63394555 |
Periodic limb movement disorder | 18.43 | 11.49 | 8 | 76297 | 246 | 63412471 |
Prescribed overdose | 18.40 | 11.49 | 9 | 76296 | 34144 | 63378573 |
Exposure to fungus | 18.23 | 11.49 | 7 | 76298 | 156 | 63412561 |
Flail chest | 18.20 | 11.49 | 6 | 76299 | 84 | 63412633 |
Illness | 18.20 | 11.49 | 111 | 76194 | 48948 | 63363769 |
Migraine | 18.11 | 11.49 | 197 | 76108 | 103149 | 63309568 |
Drug reaction with eosinophilia and systemic symptoms | 18.10 | 11.49 | 9 | 76296 | 33827 | 63378890 |
Angioedema | 18.10 | 11.49 | 109 | 76196 | 47856 | 63364861 |
Deformity | 18.06 | 11.49 | 42 | 76263 | 11642 | 63401075 |
Hippocampal sclerosis | 17.89 | 11.49 | 6 | 76299 | 89 | 63412628 |
Stomatitis | 17.77 | 11.49 | 96 | 76209 | 138629 | 63274088 |
Increased upper airway secretion | 17.76 | 11.49 | 22 | 76283 | 3650 | 63409067 |
Purpura senile | 17.61 | 11.49 | 10 | 76295 | 553 | 63412164 |
Cardiac failure | 17.57 | 11.49 | 52 | 76253 | 89090 | 63323627 |
Tarsal tunnel syndrome | 17.43 | 11.49 | 10 | 76295 | 564 | 63412153 |
Wound complication | 17.40 | 11.49 | 22 | 76283 | 3725 | 63408992 |
Eosinophil count abnormal | 17.21 | 11.49 | 10 | 76295 | 578 | 63412139 |
Ulcer | 17.20 | 11.49 | 5 | 76300 | 26102 | 63386615 |
Sedation | 17.04 | 11.49 | 13 | 76292 | 38796 | 63373921 |
Drug-induced liver injury | 17 | 11.49 | 14 | 76291 | 40208 | 63372509 |
Intentional self-injury | 16.78 | 11.49 | 5 | 76300 | 25682 | 63387035 |
Schizophrenia | 16.75 | 11.49 | 37 | 76268 | 9915 | 63402802 |
Live birth | 16.72 | 11.49 | 5 | 76300 | 25625 | 63387092 |
Erythema marginatum | 16.48 | 11.49 | 4 | 76301 | 16 | 63412701 |
Body temperature abnormal | 16.46 | 11.49 | 16 | 76289 | 2025 | 63410692 |
Depressed level of consciousness | 16.40 | 11.49 | 31 | 76274 | 62047 | 63350670 |
Shock | 16.39 | 11.49 | 4 | 76301 | 23459 | 63389258 |
Nasal oedema | 16.32 | 11.49 | 14 | 76291 | 1508 | 63411209 |
Bronchitis chronic | 16.29 | 11.49 | 23 | 76282 | 4330 | 63408387 |
Product leakage | 16.27 | 11.49 | 11 | 76294 | 830 | 63411887 |
Exercise tolerance decreased | 16.23 | 11.49 | 26 | 76279 | 5471 | 63407246 |
Hypocalcaemia | 16.13 | 11.49 | 9 | 76296 | 31704 | 63381013 |
Bronchial irritation | 16.10 | 11.49 | 4 | 76301 | 18 | 63412699 |
Paranasal sinus inflammation | 16.04 | 11.49 | 9 | 76296 | 486 | 63412231 |
Joint stiffness | 16.00 | 11.49 | 16 | 76289 | 41853 | 63370864 |
Dystrophic calcification | 15.87 | 11.49 | 6 | 76299 | 128 | 63412589 |
Cytomegalovirus infection | 15.80 | 11.49 | 3 | 76302 | 20949 | 63391768 |
Accident | 15.75 | 11.49 | 27 | 76278 | 6005 | 63406712 |
Post-traumatic stress disorder | 15.73 | 11.49 | 25 | 76280 | 5226 | 63407491 |
Bradycardia | 15.71 | 11.49 | 41 | 76264 | 73186 | 63339531 |
Sleep disorder due to general medical condition, insomnia type | 15.70 | 11.49 | 24 | 76281 | 52193 | 63360524 |
Hypertension | 15.65 | 11.49 | 443 | 75862 | 278860 | 63133857 |
Hepatic function abnormal | 15.61 | 11.49 | 13 | 76292 | 37129 | 63375588 |
Anaphylactic reaction | 15.52 | 11.49 | 134 | 76171 | 65966 | 63346751 |
Calculus urinary | 15.39 | 11.49 | 13 | 76292 | 1371 | 63411346 |
Tongue pruritus | 15.35 | 11.49 | 9 | 76296 | 529 | 63412188 |
Urticaria | 15.24 | 11.49 | 282 | 76023 | 165520 | 63247197 |
Neoplasm progression | 15.00 | 11.49 | 13 | 76292 | 36415 | 63376302 |
Genital rash | 14.95 | 11.49 | 9 | 76296 | 555 | 63412162 |
Heart rate increased | 14.87 | 11.49 | 176 | 76129 | 94062 | 63318655 |
Hospitalisation | 14.82 | 11.49 | 162 | 76143 | 84919 | 63327798 |
Temporal lobe epilepsy | 14.77 | 11.49 | 8 | 76297 | 403 | 63412314 |
Focal segmental glomerulosclerosis | 14.73 | 11.49 | 13 | 76292 | 1455 | 63411262 |
Tubulointerstitial nephritis | 14.70 | 11.49 | 3 | 76302 | 19900 | 63392817 |
Procedural anxiety | 14.66 | 11.49 | 10 | 76295 | 766 | 63411951 |
Breast cancer | 14.63 | 11.49 | 104 | 76201 | 48279 | 63364438 |
Exostosis | 14.60 | 11.49 | 51 | 76254 | 17811 | 63394906 |
Tenosynovitis | 14.56 | 11.49 | 43 | 76262 | 13752 | 63398965 |
Blood immunoglobulin E decreased | 14.56 | 11.49 | 5 | 76300 | 80 | 63412637 |
Adrenal insufficiency | 14.52 | 11.49 | 51 | 76254 | 17864 | 63394853 |
Bronchial wall thickening | 14.49 | 11.49 | 13 | 76292 | 1486 | 63411231 |
Allergy to animal | 14.47 | 11.49 | 12 | 76293 | 1234 | 63411483 |
Thoracic operation | 14.42 | 11.49 | 6 | 76299 | 166 | 63412551 |
Panic attack | 14.32 | 11.49 | 59 | 76246 | 22272 | 63390445 |
Respiratory arrest | 14.25 | 11.49 | 11 | 76294 | 32634 | 63380083 |
Asthmatic crisis | 14.22 | 11.49 | 14 | 76291 | 1799 | 63410918 |
Pregnancy | 14.16 | 11.49 | 14 | 76291 | 36822 | 63375895 |
Hypothalamic pituitary adrenal axis suppression | 14.15 | 11.49 | 6 | 76299 | 174 | 63412543 |
Diaphragmatic paralysis | 14.12 | 11.49 | 9 | 76296 | 615 | 63412102 |
Haemorrhage | 14.00 | 11.49 | 33 | 76272 | 60989 | 63351728 |
Pulmonary mass | 13.94 | 11.49 | 59 | 76246 | 22537 | 63390180 |
Hypokalaemia | 13.76 | 11.49 | 71 | 76234 | 103733 | 63308984 |
Sputum purulent | 13.74 | 11.49 | 11 | 76294 | 1076 | 63411641 |
Device expulsion | 13.74 | 11.49 | 13 | 76292 | 34909 | 63377808 |
Hereditary angioedema | 13.74 | 11.49 | 29 | 76276 | 7533 | 63405184 |
Atrial fibrillation | 13.70 | 11.49 | 83 | 76222 | 116553 | 63296164 |
Foetal exposure during pregnancy | 13.66 | 11.49 | 11 | 76294 | 31951 | 63380766 |
Skin wrinkling | 13.46 | 11.49 | 11 | 76294 | 1108 | 63411609 |
Rhinitis perennial | 13.45 | 11.49 | 4 | 76301 | 39 | 63412678 |
Product administration error | 13.45 | 11.49 | 58 | 76247 | 22339 | 63390378 |
Hypomagnesaemia | 13.44 | 11.49 | 9 | 76296 | 28728 | 63383989 |
Allergic sinusitis | 13.44 | 11.49 | 11 | 76294 | 1111 | 63411606 |
Diabetic ketoacidosis | 13.37 | 11.49 | 4 | 76301 | 20501 | 63392216 |
Hypoglycaemia | 13.37 | 11.49 | 33 | 76272 | 60032 | 63352685 |
Cerebral infarction | 13.33 | 11.49 | 6 | 76299 | 23887 | 63388830 |
Pancreatitis relapsing | 13.22 | 11.49 | 10 | 76295 | 900 | 63411817 |
Mesenteric haemorrhage | 13.18 | 11.49 | 4 | 76301 | 42 | 63412675 |
Oropharyngeal oedema | 13.12 | 11.49 | 7 | 76298 | 342 | 63412375 |
Vestibular disorder | 13.03 | 11.49 | 12 | 76293 | 1419 | 63411298 |
Influenza | 12.97 | 11.49 | 193 | 76112 | 108529 | 63304188 |
Prescribed underdose | 12.97 | 11.49 | 10 | 76295 | 29679 | 63383038 |
Stress urinary incontinence | 12.85 | 11.49 | 15 | 76290 | 2340 | 63410377 |
Unresponsive to stimuli | 12.83 | 11.49 | 13 | 76292 | 33803 | 63378914 |
Peritoneal perforation | 12.64 | 11.49 | 5 | 76300 | 121 | 63412596 |
Chronic sinusitis | 12.59 | 11.49 | 39 | 76266 | 12804 | 63399913 |
Fractional exhaled nitric oxide increased | 12.36 | 11.49 | 3 | 76302 | 12 | 63412705 |
Dry throat | 12.36 | 11.49 | 26 | 76279 | 6739 | 63405978 |
Aphonia | 12.22 | 11.49 | 33 | 76272 | 10030 | 63402687 |
Product deposit | 12.22 | 11.49 | 6 | 76299 | 246 | 63412471 |
Exposure via skin contact | 12.15 | 11.49 | 7 | 76298 | 398 | 63412319 |
Drug eruption | 12.11 | 11.49 | 10 | 76295 | 28684 | 63384033 |
Ascites | 11.98 | 11.49 | 19 | 76286 | 40709 | 63372008 |
Infusion site pruritus | 11.97 | 11.49 | 24 | 76281 | 6011 | 63406706 |
Breast conserving surgery | 11.97 | 11.49 | 10 | 76295 | 1039 | 63411678 |
Infusion site erythema | 11.95 | 11.49 | 36 | 76269 | 11643 | 63401074 |
Seizure | 11.89 | 11.49 | 102 | 76203 | 132532 | 63280185 |
Intraocular pressure increased | 11.86 | 11.49 | 24 | 76281 | 6054 | 63406663 |
Bone hypertrophy | 11.85 | 11.49 | 7 | 76298 | 417 | 63412300 |
Product administered to patient of inappropriate age | 11.84 | 11.49 | 17 | 76288 | 3251 | 63409466 |
Infusion site swelling | 11.83 | 11.49 | 32 | 76273 | 9738 | 63402979 |
Breath sounds absent | 11.77 | 11.49 | 6 | 76299 | 267 | 63412450 |
Toxic epidermal necrolysis | 11.76 | 11.49 | 8 | 76297 | 25326 | 63387391 |
Ear pain | 11.72 | 11.49 | 79 | 76226 | 36039 | 63376678 |
Respiratory failure | 11.70 | 11.49 | 73 | 76232 | 101785 | 63310932 |
Metastases to liver | 11.61 | 11.49 | 7 | 76298 | 23632 | 63389085 |
Pneumocystis jirovecii pneumonia | 11.59 | 11.49 | 3 | 76302 | 16911 | 63395806 |
Rhabdomyolysis | 11.56 | 11.49 | 22 | 76283 | 43929 | 63368788 |
Erythema of eyelid | 11.55 | 11.49 | 14 | 76291 | 2272 | 63410445 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Product quality issue | 2851.29 | 12.16 | 929 | 32682 | 16106 | 34907214 |
No adverse event | 2191.50 | 12.16 | 824 | 32787 | 22103 | 34901217 |
Poor quality device used | 1475.43 | 12.16 | 306 | 33305 | 644 | 34922676 |
Product dose omission issue | 1062.83 | 12.16 | 894 | 32717 | 118817 | 34804503 |
Asthma | 535.74 | 12.16 | 392 | 33219 | 42264 | 34881056 |
Product container issue | 423.28 | 12.16 | 105 | 33506 | 614 | 34922706 |
Device malfunction | 379.57 | 12.16 | 190 | 33421 | 10231 | 34913089 |
Wheezing | 373.37 | 12.16 | 313 | 33298 | 41089 | 34882231 |
Circumstance or information capable of leading to medication error | 268.50 | 12.16 | 90 | 33521 | 1689 | 34921631 |
Cough | 197.16 | 12.16 | 441 | 33170 | 149699 | 34773621 |
Chest discomfort | 196.65 | 12.16 | 252 | 33359 | 54278 | 34869042 |
Obstructive airways disorder | 173.26 | 12.16 | 133 | 33478 | 15361 | 34907959 |
Nasal congestion | 159.20 | 12.16 | 150 | 33461 | 22907 | 34900413 |
Nasal polyps | 158.34 | 12.16 | 67 | 33544 | 2436 | 34920884 |
Dyspnoea | 155.89 | 12.16 | 744 | 32867 | 376038 | 34547282 |
Sleep disorder due to a general medical condition | 132.90 | 12.16 | 75 | 33536 | 5146 | 34918174 |
Fractional exhaled nitric oxide increased | 125.59 | 12.16 | 45 | 33566 | 1037 | 34922283 |
Toxicity to various agents | 107.25 | 12.16 | 30 | 33581 | 200332 | 34722988 |
Plantar fasciitis | 99.51 | 12.16 | 46 | 33565 | 2070 | 34921250 |
Death | 96.86 | 12.16 | 146 | 33465 | 397903 | 34525417 |
Chronic sinusitis | 96.25 | 12.16 | 46 | 33565 | 2233 | 34921087 |
Sensation of foreign body | 93.28 | 12.16 | 48 | 33563 | 2735 | 34920585 |
Full blood count abnormal | 91.54 | 12.16 | 101 | 33510 | 18567 | 34904753 |
Infective pulmonary exacerbation of cystic fibrosis | 90.87 | 12.16 | 65 | 33546 | 6736 | 34916584 |
Sinusitis | 87.65 | 12.16 | 149 | 33462 | 41253 | 34882067 |
Acute kidney injury | 87.31 | 12.16 | 99 | 33512 | 304889 | 34618431 |
Myoglobin blood increased | 83.97 | 12.16 | 46 | 33565 | 2977 | 34920343 |
Dyspnoea exertional | 79.04 | 12.16 | 146 | 33465 | 43133 | 34880187 |
Drug abuse | 72.81 | 12.16 | 6 | 33605 | 99090 | 34824230 |
Off label use | 72.55 | 12.16 | 188 | 33423 | 419336 | 34503984 |
Rhinitis perennial | 71.78 | 12.16 | 22 | 33589 | 305 | 34923015 |
Productive cough | 70.85 | 12.16 | 129 | 33482 | 37684 | 34885636 |
Neutropenia | 67.82 | 12.16 | 33 | 33578 | 156745 | 34766575 |
Upper-airway cough syndrome | 66.77 | 12.16 | 42 | 33569 | 3516 | 34919804 |
Completed suicide | 66.76 | 12.16 | 8 | 33603 | 98160 | 34825160 |
Secretion discharge | 66.67 | 12.16 | 51 | 33560 | 5854 | 34917466 |
Steroid withdrawal syndrome | 64.58 | 12.16 | 19 | 33592 | 227 | 34923093 |
Brain natriuretic peptide increased | 61.97 | 12.16 | 48 | 33563 | 5611 | 34917709 |
Nasopharyngitis | 61.68 | 12.16 | 177 | 33434 | 69791 | 34853529 |
Nasal discomfort | 60.17 | 12.16 | 30 | 33581 | 1598 | 34921722 |
Anosmia | 59.67 | 12.16 | 41 | 33570 | 3983 | 34919337 |
Thrombocytopenia | 58.82 | 12.16 | 39 | 33572 | 156208 | 34767112 |
Dysphonia | 57.39 | 12.16 | 90 | 33521 | 23293 | 34900027 |
Eosinophilic granulomatosis with polyangiitis | 57.31 | 12.16 | 31 | 33580 | 1956 | 34921364 |
Exostosis | 55.99 | 12.16 | 42 | 33569 | 4681 | 34918639 |
Poor quality product administered | 55.69 | 12.16 | 30 | 33581 | 1877 | 34921443 |
Dermatitis atopic | 51.38 | 12.16 | 42 | 33569 | 5305 | 34918015 |
Hypersensitivity | 50.52 | 12.16 | 151 | 33460 | 60884 | 34862436 |
Dust allergy | 49.92 | 12.16 | 22 | 33589 | 884 | 34922436 |
Incorrect dose administered | 49.62 | 12.16 | 116 | 33495 | 40399 | 34882921 |
Anaemia | 47.96 | 12.16 | 95 | 33516 | 233240 | 34690080 |
Adjustment disorder | 46.97 | 12.16 | 23 | 33588 | 1178 | 34922142 |
Underdose | 46.96 | 12.16 | 62 | 33549 | 13718 | 34909602 |
Product taste abnormal | 44.47 | 12.16 | 22 | 33589 | 1152 | 34922168 |
Forced expiratory volume decreased | 43.68 | 12.16 | 31 | 33580 | 3172 | 34920148 |
Rhinorrhoea | 43.62 | 12.16 | 84 | 33527 | 25584 | 34897736 |
Painful respiration | 43.40 | 12.16 | 22 | 33589 | 1214 | 34922106 |
Bronchopulmonary aspergillosis allergic | 43.07 | 12.16 | 20 | 33591 | 909 | 34922411 |
Device dislocation | 41.85 | 12.16 | 40 | 33571 | 6209 | 34917111 |
Rhinitis allergic | 40.39 | 12.16 | 29 | 33582 | 3021 | 34920299 |
Adrenal suppression | 39.86 | 12.16 | 17 | 33594 | 630 | 34922690 |
Obesity | 39.42 | 12.16 | 55 | 33556 | 12823 | 34910497 |
Chest injury | 38.19 | 12.16 | 22 | 33589 | 1569 | 34921751 |
Bronchial obstruction | 37.87 | 12.16 | 22 | 33589 | 1594 | 34921726 |
Sinus polyp | 37.80 | 12.16 | 12 | 33599 | 188 | 34923132 |
Pulmonary function test decreased | 37.48 | 12.16 | 34 | 33577 | 4941 | 34918379 |
Platelet count decreased | 37.36 | 12.16 | 36 | 33575 | 119681 | 34803639 |
Pleural thickening | 37.23 | 12.16 | 14 | 33597 | 371 | 34922949 |
Nasal disorder | 36.78 | 12.16 | 23 | 33588 | 1905 | 34921415 |
Renal failure | 36.56 | 12.16 | 43 | 33568 | 130514 | 34792806 |
Eosinophilia | 35.35 | 12.16 | 78 | 33533 | 26144 | 34897176 |
Multiple organ dysfunction syndrome | 34.81 | 12.16 | 15 | 33596 | 76551 | 34846769 |
Oropharyngeal discomfort | 34.76 | 12.16 | 27 | 33584 | 3169 | 34920151 |
Therapeutic product effect incomplete | 34.47 | 12.16 | 117 | 33494 | 50424 | 34872896 |
Allergy to animal | 32.87 | 12.16 | 13 | 33598 | 396 | 34922924 |
Hyperkalaemia | 32.50 | 12.16 | 13 | 33598 | 69376 | 34853944 |
Walking aid user | 31.87 | 12.16 | 21 | 33590 | 1903 | 34921417 |
Hepatic function abnormal | 31.72 | 12.16 | 3 | 33608 | 44360 | 34878960 |
Gastrooesophageal reflux disease | 31.53 | 12.16 | 94 | 33517 | 37830 | 34885490 |
Febrile neutropenia | 31.40 | 12.16 | 52 | 33559 | 136797 | 34786523 |
Disease progression | 30.90 | 12.16 | 35 | 33576 | 108042 | 34815278 |
Nasal oedema | 30.58 | 12.16 | 12 | 33599 | 358 | 34922962 |
Oropharyngeal pain | 30.50 | 12.16 | 89 | 33522 | 35396 | 34887924 |
Middle insomnia | 30.26 | 12.16 | 35 | 33576 | 6767 | 34916553 |
Loss of personal independence in daily activities | 30.24 | 12.16 | 85 | 33526 | 33094 | 34890226 |
Enterocolitis infectious | 29.30 | 12.16 | 19 | 33592 | 1676 | 34921644 |
Eczema | 28.50 | 12.16 | 58 | 33553 | 18378 | 34904942 |
Bradycardia | 28.11 | 12.16 | 19 | 33592 | 75399 | 34847921 |
Malignant neoplasm progression | 28.01 | 12.16 | 26 | 33585 | 88020 | 34835300 |
Respiratory tract congestion | 28.00 | 12.16 | 32 | 33579 | 6107 | 34917213 |
Drug interaction | 27.99 | 12.16 | 117 | 33494 | 225829 | 34697491 |
Tachyarrhythmia | 27.85 | 12.16 | 25 | 33586 | 3583 | 34919737 |
Bronchial wall thickening | 27.82 | 12.16 | 17 | 33594 | 1351 | 34921969 |
Seasonal allergy | 27.46 | 12.16 | 33 | 33578 | 6642 | 34916678 |
Pancytopenia | 27.00 | 12.16 | 31 | 33580 | 95126 | 34828194 |
Sleep apnoea syndrome | 26.88 | 12.16 | 60 | 33551 | 20261 | 34903059 |
General physical health deterioration | 26.50 | 12.16 | 52 | 33559 | 128217 | 34795103 |
Influenza | 26.33 | 12.16 | 106 | 33505 | 49560 | 34873760 |
Throat irritation | 26.32 | 12.16 | 41 | 33570 | 10544 | 34912776 |
Hypersomnia | 25.37 | 12.16 | 44 | 33567 | 12363 | 34910957 |
Product odour abnormal | 24.90 | 12.16 | 13 | 33598 | 763 | 34922557 |
Sputum discoloured | 24.86 | 12.16 | 34 | 33577 | 7778 | 34915542 |
Cardio-respiratory arrest | 24.85 | 12.16 | 11 | 33600 | 55262 | 34868058 |
Oral candidiasis | 24.84 | 12.16 | 43 | 33568 | 12067 | 34911253 |
Central obesity | 24.72 | 12.16 | 12 | 33599 | 603 | 34922717 |
Skin plaque | 24.42 | 12.16 | 26 | 33585 | 4588 | 34918732 |
Tongue dry | 24.20 | 12.16 | 9 | 33602 | 231 | 34923089 |
Increased viscosity of upper respiratory secretion | 24.12 | 12.16 | 8 | 33603 | 145 | 34923175 |
Chorioretinopathy | 24.02 | 12.16 | 16 | 33595 | 1477 | 34921843 |
Product quality control issue | 23.79 | 12.16 | 4 | 33607 | 0 | 34923320 |
Hypotension | 23.75 | 12.16 | 121 | 33490 | 221528 | 34701792 |
Sneezing | 23.36 | 12.16 | 27 | 33584 | 5215 | 34918105 |
Ear infection | 23.20 | 12.16 | 38 | 33573 | 10193 | 34913127 |
Septic shock | 23.10 | 12.16 | 21 | 33590 | 71813 | 34851507 |
Pyrexia | 23.09 | 12.16 | 207 | 33404 | 332806 | 34590514 |
Sepsis | 22.68 | 12.16 | 83 | 33528 | 166478 | 34756842 |
Hot flush | 22.41 | 12.16 | 52 | 33559 | 18014 | 34905306 |
Rhinitis | 22.34 | 12.16 | 29 | 33582 | 6309 | 34917011 |
Aortic aneurysm | 22.33 | 12.16 | 30 | 33581 | 6749 | 34916571 |
Leukopenia | 21.90 | 12.16 | 17 | 33594 | 62839 | 34860481 |
Renal impairment | 21.59 | 12.16 | 36 | 33575 | 94477 | 34828843 |
Wrong technique in device usage process | 21.47 | 12.16 | 15 | 33596 | 1497 | 34921823 |
Encephalopathy | 21.42 | 12.16 | 4 | 33607 | 35315 | 34888005 |
Cardiac disorder | 21.25 | 12.16 | 90 | 33521 | 43036 | 34880284 |
Eosinophilic bronchitis | 21.14 | 12.16 | 8 | 33603 | 216 | 34923104 |
Exercise lack of | 20.99 | 12.16 | 7 | 33604 | 129 | 34923191 |
Feeling cold | 20.81 | 12.16 | 37 | 33574 | 10602 | 34912718 |
Discomfort | 20.79 | 12.16 | 52 | 33559 | 18886 | 34904434 |
Metabolic acidosis | 20.75 | 12.16 | 8 | 33603 | 43672 | 34879648 |
Mast cell activation syndrome | 20.28 | 12.16 | 8 | 33603 | 242 | 34923078 |
Bronchitis | 20.23 | 12.16 | 87 | 33524 | 41876 | 34881444 |
Headache | 20.06 | 12.16 | 287 | 33324 | 200348 | 34722972 |
Blood creatinine increased | 20.04 | 12.16 | 38 | 33573 | 94938 | 34828382 |
Interstitial lung disease | 19.92 | 12.16 | 20 | 33591 | 65262 | 34858058 |
Ascites | 19.81 | 12.16 | 10 | 33601 | 46561 | 34876759 |
Somnolence | 19.69 | 12.16 | 49 | 33562 | 111067 | 34812253 |
Maple syrup disease | 19.41 | 12.16 | 4 | 33607 | 8 | 34923312 |
Temperature intolerance | 19.39 | 12.16 | 20 | 33591 | 3402 | 34919918 |
Dry skin | 19.23 | 12.16 | 70 | 33541 | 31217 | 34892103 |
Incorrect dose administered by product | 19.02 | 12.16 | 5 | 33606 | 38 | 34923282 |
Fungal disease carrier | 18.95 | 12.16 | 8 | 33603 | 289 | 34923031 |
Diarrhoea | 18.85 | 12.16 | 263 | 33348 | 389649 | 34533671 |
Bronchiolitis | 18.79 | 12.16 | 19 | 33592 | 3157 | 34920163 |
Growth retardation | 18.78 | 12.16 | 15 | 33596 | 1833 | 34921487 |
Product availability issue | 18.50 | 12.16 | 15 | 33596 | 1872 | 34921448 |
Cockroach allergy | 18.47 | 12.16 | 5 | 33606 | 43 | 34923277 |
Confusional state | 18.23 | 12.16 | 74 | 33537 | 144086 | 34779234 |
Sitting disability | 18.22 | 12.16 | 7 | 33604 | 197 | 34923123 |
Cardiac arrest | 18.16 | 12.16 | 41 | 33570 | 96118 | 34827202 |
Cystic fibrosis | 18.01 | 12.16 | 14 | 33597 | 1644 | 34921676 |
Respiratory arrest | 17.38 | 12.16 | 3 | 33608 | 28040 | 34895280 |
Gastrointestinal haemorrhage | 17.30 | 12.16 | 37 | 33574 | 88440 | 34834880 |
Skin atrophy | 17.12 | 12.16 | 15 | 33596 | 2082 | 34921238 |
Sleep disorder | 17.08 | 12.16 | 68 | 33543 | 31620 | 34891700 |
Sinus disorder | 17.00 | 12.16 | 27 | 33584 | 7058 | 34916262 |
Crepitations | 16.90 | 12.16 | 18 | 33593 | 3178 | 34920142 |
Conjunctivitis | 16.77 | 12.16 | 32 | 33579 | 9673 | 34913647 |
Myocardial infarction | 16.70 | 12.16 | 60 | 33551 | 121025 | 34802295 |
Cataract | 16.44 | 12.16 | 59 | 33552 | 26127 | 34897193 |
Papillary renal cell carcinoma | 16.37 | 12.16 | 7 | 33604 | 261 | 34923059 |
Coma | 16.37 | 12.16 | 12 | 33599 | 45666 | 34877654 |
Transaminases increased | 16.34 | 12.16 | 3 | 33608 | 26820 | 34896500 |
Intentional overdose | 16.27 | 12.16 | 11 | 33600 | 43663 | 34879657 |
Expired product administered | 16.24 | 12.16 | 18 | 33593 | 3323 | 34919997 |
Snoring | 16.21 | 12.16 | 18 | 33593 | 3328 | 34919992 |
C-reactive protein increased | 16.02 | 12.16 | 17 | 33594 | 54081 | 34869239 |
Ear disorder | 15.66 | 12.16 | 13 | 33598 | 1677 | 34921643 |
Bronchial irritation | 15.63 | 12.16 | 4 | 33607 | 27 | 34923293 |
Hepatic failure | 15.32 | 12.16 | 7 | 33604 | 34524 | 34888796 |
Pleural effusion | 15.21 | 12.16 | 35 | 33576 | 81511 | 34841809 |
Rhabdomyolysis | 14.62 | 12.16 | 27 | 33584 | 68136 | 34855184 |
Cholestasis | 14.44 | 12.16 | 4 | 33607 | 26944 | 34896376 |
Aspartate aminotransferase increased | 14.40 | 12.16 | 27 | 33584 | 67756 | 34855564 |
Dyspnoea at rest | 14.26 | 12.16 | 18 | 33593 | 3810 | 34919510 |
Chronic obstructive pulmonary disease | 14.19 | 12.16 | 88 | 33523 | 48830 | 34874490 |
Bronchiectasis | 14.17 | 12.16 | 30 | 33581 | 9771 | 34913549 |
Hyposmia | 14.10 | 12.16 | 6 | 33605 | 221 | 34923099 |
Polyp | 14.02 | 12.16 | 18 | 33593 | 3874 | 34919446 |
Lactic acidosis | 14.00 | 12.16 | 8 | 33603 | 34764 | 34888556 |
Delirium | 13.97 | 12.16 | 13 | 33598 | 43978 | 34879342 |
Swollen tongue | 13.88 | 12.16 | 38 | 33573 | 14567 | 34908753 |
Cytomegalovirus infection | 13.79 | 12.16 | 4 | 33607 | 26131 | 34897189 |
Hyperleukocytosis | 13.76 | 12.16 | 13 | 33598 | 1989 | 34921331 |
Pruritus | 13.73 | 12.16 | 202 | 33409 | 141779 | 34781541 |
Drug resistance | 13.62 | 12.16 | 4 | 33607 | 25923 | 34897397 |
Treatment failure | 13.47 | 12.16 | 15 | 33596 | 46682 | 34876638 |
Haemoglobin decreased | 13.44 | 12.16 | 65 | 33546 | 120707 | 34802613 |
Blood pressure decreased | 13.33 | 12.16 | 18 | 33593 | 51497 | 34871823 |
Lung diffusion disorder | 12.97 | 12.16 | 5 | 33606 | 142 | 34923178 |
Hypercholesterolaemia | 12.88 | 12.16 | 27 | 33584 | 8735 | 34914585 |
Coronary artery disease | 12.84 | 12.16 | 85 | 33526 | 48220 | 34875100 |
International normalised ratio increased | 12.79 | 12.16 | 16 | 33595 | 47311 | 34876009 |
Primary familial brain calcification | 12.48 | 12.16 | 3 | 33608 | 15 | 34923305 |
Skin weeping | 12.31 | 12.16 | 7 | 33604 | 487 | 34922833 |
Haematochezia | 12.30 | 12.16 | 16 | 33595 | 46518 | 34876802 |
Sputum abnormal | 12.26 | 12.16 | 7 | 33604 | 491 | 34922829 |
Pleuritic pain | 12.17 | 12.16 | 16 | 33595 | 3525 | 34919795 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Product quality issue | 2000.33 | 10.20 | 882 | 81655 | 33058 | 79628793 |
Poor quality device used | 1994.45 | 10.20 | 465 | 82072 | 1820 | 79660031 |
Asthma | 1045.03 | 10.20 | 966 | 81571 | 134129 | 79527722 |
Wheezing | 660.01 | 10.20 | 704 | 81833 | 115960 | 79545891 |
No adverse event | 644.72 | 10.20 | 429 | 82108 | 36763 | 79625088 |
Product dose omission issue | 595.49 | 10.20 | 981 | 81556 | 246556 | 79415295 |
Gastrooesophageal reflux disease | 564.84 | 10.20 | 615 | 81922 | 103631 | 79558220 |
Device malfunction | 472.75 | 10.20 | 288 | 82249 | 21160 | 79640691 |
Rhinitis allergic | 426.15 | 10.20 | 222 | 82315 | 12047 | 79649804 |
Sleep disorder due to a general medical condition | 397.29 | 10.20 | 223 | 82314 | 14054 | 79647797 |
Cough | 345.66 | 10.20 | 995 | 81542 | 365794 | 79296057 |
Nasal polyps | 314.39 | 10.20 | 153 | 82384 | 7174 | 79654677 |
Ejection fraction | 307.88 | 10.20 | 108 | 82429 | 2161 | 79659690 |
Circumstance or information capable of leading to medication error | 303.34 | 10.20 | 124 | 82413 | 3824 | 79658027 |
Sputum discoloured | 297.50 | 10.20 | 217 | 82320 | 21526 | 79640325 |
Polycystic ovaries | 294.83 | 10.20 | 120 | 82417 | 3659 | 79658192 |
Sensitisation | 292.53 | 10.20 | 115 | 82422 | 3196 | 79658655 |
Dyspnoea | 268.47 | 10.20 | 1656 | 80881 | 855369 | 78806482 |
Nasal congestion | 257.10 | 10.20 | 355 | 82182 | 76197 | 79585654 |
Productive cough | 253.30 | 10.20 | 380 | 82157 | 87951 | 79573900 |
Product container issue | 240.59 | 10.20 | 78 | 82459 | 1213 | 79660638 |
Full blood count abnormal | 240.54 | 10.20 | 251 | 82286 | 40223 | 79621628 |
Toxicity to various agents | 237.20 | 10.20 | 71 | 82466 | 421469 | 79240382 |
Completed suicide | 222.60 | 10.20 | 7 | 82530 | 245760 | 79416091 |
Blood test abnormal | 220.44 | 10.20 | 167 | 82370 | 17543 | 79644308 |
Obstructive airways disorder | 192.15 | 10.20 | 198 | 82339 | 31261 | 79630590 |
Chest discomfort | 184.94 | 10.20 | 428 | 82109 | 137616 | 79524235 |
Infective pulmonary exacerbation of cystic fibrosis | 184.32 | 10.20 | 132 | 82405 | 12719 | 79649132 |
Acute kidney injury | 161.43 | 10.20 | 180 | 82357 | 519224 | 79142627 |
Sleep apnoea syndrome | 159.79 | 10.20 | 193 | 82344 | 36285 | 79625566 |
Pleural thickening | 154.75 | 10.20 | 71 | 82466 | 2911 | 79658940 |
Death | 147.60 | 10.20 | 224 | 82313 | 566290 | 79095561 |
Synovitis | 141.30 | 10.20 | 3 | 82534 | 150731 | 79511120 |
Steroid withdrawal syndrome | 140.23 | 10.20 | 45 | 82492 | 676 | 79661175 |
Drug abuse | 139.28 | 10.20 | 7 | 82530 | 162684 | 79499167 |
Bronchiectasis | 138.70 | 10.20 | 142 | 82395 | 22244 | 79639607 |
Presbyacusis | 136.99 | 10.20 | 63 | 82474 | 2597 | 79659254 |
Bronchopulmonary aspergillosis allergic | 134.57 | 10.20 | 65 | 82472 | 2996 | 79658855 |
Neutropenia | 132.67 | 10.20 | 66 | 82471 | 287644 | 79374207 |
Carpal tunnel syndrome | 130.39 | 10.20 | 129 | 82408 | 19399 | 79642452 |
Headache | 118.70 | 10.20 | 1113 | 81424 | 652659 | 79009192 |
Therapeutic product effect incomplete | 113.92 | 10.20 | 364 | 82173 | 141281 | 79520570 |
Total lung capacity increased | 113.90 | 10.20 | 53 | 82484 | 2245 | 79659606 |
Pleural fibrosis | 112.96 | 10.20 | 64 | 82473 | 4103 | 79657748 |
Sinusitis | 111.59 | 10.20 | 449 | 82088 | 195052 | 79466799 |
Asthma-chronic obstructive pulmonary disease overlap syndrome | 108.17 | 10.20 | 57 | 82480 | 3164 | 79658687 |
Off label use | 106.31 | 10.20 | 531 | 82006 | 906684 | 78755167 |
Thrombocytopenia | 103.77 | 10.20 | 74 | 82463 | 265185 | 79396666 |
Blood magnesium increased | 98.16 | 10.20 | 55 | 82482 | 3451 | 79658400 |
Pneumonia aspiration | 97.83 | 10.20 | 215 | 82322 | 66752 | 79595099 |
Loss of personal independence in daily activities | 96.91 | 10.20 | 279 | 82258 | 102301 | 79559550 |
Ejection fraction abnormal | 95.89 | 10.20 | 48 | 82489 | 2392 | 79659459 |
Eosinophilic granulomatosis with polyangiitis | 93.29 | 10.20 | 54 | 82483 | 3606 | 79658245 |
Deafness neurosensory | 92.42 | 10.20 | 68 | 82469 | 6830 | 79655021 |
Burning sensation | 92.25 | 10.20 | 194 | 82343 | 58438 | 79603413 |
Rhinorrhoea | 92.22 | 10.20 | 227 | 82310 | 75847 | 79586004 |
Nephrectomy | 90.23 | 10.20 | 44 | 82493 | 2071 | 79659780 |
Nasal discomfort | 87.19 | 10.20 | 60 | 82477 | 5423 | 79656428 |
Anaemia | 86.04 | 10.20 | 210 | 82327 | 444805 | 79217046 |
Contraindicated product administered | 85.83 | 10.20 | 28 | 82509 | 157510 | 79504341 |
Hand deformity | 84.30 | 10.20 | 6 | 82531 | 103913 | 79557938 |
Upper-airway cough syndrome | 83.22 | 10.20 | 80 | 82457 | 11613 | 79650238 |
Anosmia | 81.58 | 10.20 | 70 | 82467 | 8774 | 79653077 |
Sinus disorder | 81.16 | 10.20 | 108 | 82429 | 22356 | 79639495 |
Forced expiratory volume decreased | 80.66 | 10.20 | 66 | 82471 | 7748 | 79654103 |
Bronchitis | 76.05 | 10.20 | 302 | 82235 | 130342 | 79531509 |
Cardiac disorder | 75.28 | 10.20 | 192 | 82345 | 65565 | 79596286 |
Middle insomnia | 75.27 | 10.20 | 88 | 82449 | 15981 | 79645870 |
Systemic lupus erythematosus | 74.49 | 10.20 | 17 | 82520 | 121132 | 79540719 |
Cyst | 73.68 | 10.20 | 81 | 82456 | 13759 | 79648092 |
Rhinitis perennial | 72.58 | 10.20 | 23 | 82514 | 331 | 79661520 |
Drug interaction | 72.56 | 10.20 | 206 | 82331 | 414977 | 79246874 |
Epigastric discomfort | 71.82 | 10.20 | 62 | 82475 | 7834 | 79654017 |
General physical health deterioration | 70.39 | 10.20 | 110 | 82427 | 275128 | 79386723 |
Dermatitis atopic | 70.06 | 10.20 | 68 | 82469 | 9988 | 79651863 |
Sarcoidosis | 68.92 | 10.20 | 62 | 82475 | 8273 | 79653578 |
Oropharyngeal pain | 68.72 | 10.20 | 259 | 82278 | 109094 | 79552757 |
Product taste abnormal | 67.34 | 10.20 | 37 | 82500 | 2234 | 79659617 |
Intentional overdose | 66.91 | 10.20 | 14 | 82523 | 105946 | 79555905 |
Bronchial obstruction | 65.70 | 10.20 | 39 | 82498 | 2729 | 79659122 |
Pericarditis | 65.35 | 10.20 | 14 | 82523 | 104222 | 79557629 |
Glossodynia | 64.54 | 10.20 | 14 | 82523 | 103323 | 79558528 |
Multiple organ dysfunction syndrome | 64.40 | 10.20 | 22 | 82515 | 120224 | 79541627 |
Platelet count decreased | 63.06 | 10.20 | 65 | 82472 | 194599 | 79467252 |
Rales | 63.00 | 10.20 | 90 | 82447 | 19911 | 79641940 |
Hyperkalaemia | 62.90 | 10.20 | 20 | 82517 | 114378 | 79547473 |
Osteopenia | 61.35 | 10.20 | 85 | 82452 | 18279 | 79643572 |
Nasal disorder | 59.36 | 10.20 | 41 | 82496 | 3728 | 79658123 |
Overdose | 59.11 | 10.20 | 62 | 82475 | 184144 | 79477707 |
Swollen tongue | 58.04 | 10.20 | 133 | 82404 | 42437 | 79619414 |
Febrile neutropenia | 57.46 | 10.20 | 94 | 82443 | 230905 | 79430946 |
Cardiac arrest | 57.41 | 10.20 | 56 | 82481 | 172040 | 79489811 |
Sleep disorder | 57.24 | 10.20 | 207 | 82330 | 85470 | 79576381 |
Helicobacter infection | 56.60 | 10.20 | 4 | 82533 | 69700 | 79592151 |
Pancytopenia | 56.38 | 10.20 | 53 | 82484 | 165692 | 79496159 |
Metabolic acidosis | 56.20 | 10.20 | 9 | 82528 | 82520 | 79579331 |
Bone cyst | 55.61 | 10.20 | 38 | 82499 | 3395 | 79658456 |
Dry eye | 55.55 | 10.20 | 120 | 82417 | 36811 | 79625040 |
Cardiac murmur | 55.51 | 10.20 | 75 | 82462 | 15749 | 79646102 |
Eczema | 55.07 | 10.20 | 127 | 82410 | 40691 | 79621160 |
Chronic sinusitis | 53.92 | 10.20 | 67 | 82470 | 12959 | 79648892 |
Hypothyroidism | 53.88 | 10.20 | 147 | 82390 | 52245 | 79609606 |
Adrenal suppression | 53.45 | 10.20 | 27 | 82510 | 1372 | 79660479 |
Heart sounds | 53.28 | 10.20 | 24 | 82513 | 942 | 79660909 |
Leukopenia | 53.24 | 10.20 | 27 | 82510 | 116486 | 79545365 |
Cardio-respiratory arrest | 52.89 | 10.20 | 23 | 82514 | 108487 | 79553364 |
Hypotension | 52.34 | 10.20 | 256 | 82281 | 440061 | 79221790 |
Swelling face | 51.84 | 10.20 | 177 | 82360 | 71035 | 79590816 |
Confusional state | 51.76 | 10.20 | 163 | 82374 | 317834 | 79344017 |
Renal disorder | 51.39 | 10.20 | 126 | 82411 | 41979 | 79619872 |
Disease progression | 50.71 | 10.20 | 70 | 82467 | 184292 | 79477559 |
Osteosclerosis | 50.64 | 10.20 | 38 | 82499 | 3933 | 79657918 |
Pulmonary function test decreased | 50.15 | 10.20 | 50 | 82487 | 7587 | 79654264 |
Prolonged expiration | 49.94 | 10.20 | 25 | 82512 | 1246 | 79660605 |
Rheumatoid factor positive | 49.87 | 10.20 | 3 | 82534 | 59836 | 79602015 |
Renal failure | 49.77 | 10.20 | 82 | 82455 | 200886 | 79460965 |
Dyspnoea exertional | 49.63 | 10.20 | 200 | 82337 | 86873 | 79574978 |
Chronic obstructive pulmonary disease | 49.32 | 10.20 | 197 | 82340 | 85222 | 79576629 |
Respiratory tract congestion | 49.01 | 10.20 | 80 | 82457 | 19874 | 79641977 |
Rhinitis | 48.66 | 10.20 | 68 | 82469 | 14739 | 79647112 |
Incorrect dose administered | 48.55 | 10.20 | 182 | 82355 | 76448 | 79585403 |
Dysphonia | 48.29 | 10.20 | 149 | 82388 | 56723 | 79605128 |
Wrong technique in device usage process | 47.96 | 10.20 | 37 | 82500 | 3991 | 79657860 |
Seasonal allergy | 47.57 | 10.20 | 71 | 82466 | 16335 | 79645516 |
Septic shock | 47.02 | 10.20 | 35 | 82502 | 122766 | 79539085 |
Asthenopia | 46.92 | 10.20 | 30 | 82507 | 2397 | 79659454 |
Total lung capacity decreased | 46.69 | 10.20 | 32 | 82505 | 2873 | 79658978 |
Maternal exposure during pregnancy | 44.88 | 10.20 | 45 | 82492 | 136493 | 79525358 |
Sepsis | 44.61 | 10.20 | 137 | 82400 | 269291 | 79392560 |
C-reactive protein increased | 44.18 | 10.20 | 41 | 82496 | 128986 | 79532865 |
Respiration abnormal | 43.94 | 10.20 | 47 | 82490 | 7741 | 79654110 |
Nasal mucosal disorder | 43.69 | 10.20 | 16 | 82521 | 364 | 79661487 |
Infusion related reaction | 43.36 | 10.20 | 110 | 82427 | 230127 | 79431724 |
Skin weeping | 42.33 | 10.20 | 21 | 82516 | 1026 | 79660825 |
Wound | 42.09 | 10.20 | 35 | 82502 | 116144 | 79545707 |
Lactic acidosis | 41.06 | 10.20 | 11 | 82526 | 70348 | 79591503 |
Influenza | 40.49 | 10.20 | 251 | 82286 | 129355 | 79532496 |
Hypersensitivity | 40.35 | 10.20 | 432 | 82105 | 261807 | 79400044 |
Dust allergy | 40.05 | 10.20 | 23 | 82514 | 1513 | 79660338 |
Hyponatraemia | 39.17 | 10.20 | 78 | 82459 | 177770 | 79484081 |
Breast cancer | 39.03 | 10.20 | 99 | 82438 | 33682 | 79628169 |
Joint swelling | 38.96 | 10.20 | 160 | 82377 | 288486 | 79373365 |
Palpitations | 38.80 | 10.20 | 244 | 82293 | 126366 | 79535485 |
Bone marrow failure | 38.58 | 10.20 | 4 | 82533 | 51103 | 79610748 |
Encephalopathy | 38.46 | 10.20 | 11 | 82526 | 67386 | 79594465 |
Urticaria | 37.86 | 10.20 | 324 | 82213 | 184877 | 79476974 |
Nasal oedema | 37.59 | 10.20 | 23 | 82514 | 1701 | 79660150 |
Painful respiration | 37.40 | 10.20 | 30 | 82507 | 3423 | 79658428 |
Throat irritation | 37.33 | 10.20 | 110 | 82427 | 40836 | 79621015 |
Nasopharyngitis | 37.11 | 10.20 | 414 | 82123 | 253467 | 79408384 |
Mucosal inflammation | 36.86 | 10.20 | 16 | 82521 | 75564 | 79586287 |
Tunnel vision | 36.85 | 10.20 | 22 | 82515 | 1556 | 79660295 |
Hepatic function abnormal | 36.42 | 10.20 | 15 | 82522 | 73092 | 79588759 |
Underdose | 36.08 | 10.20 | 95 | 82442 | 33056 | 79628795 |
Interstitial lung disease | 36.00 | 10.20 | 38 | 82499 | 112562 | 79549289 |
Bradycardia | 34.79 | 10.20 | 54 | 82483 | 135503 | 79526348 |
Alveolar osteitis | 34.32 | 10.20 | 17 | 82520 | 828 | 79661023 |
Increased viscosity of upper respiratory secretion | 33.87 | 10.20 | 13 | 82524 | 338 | 79661513 |
Urinary tract discomfort | 33.38 | 10.20 | 16 | 82521 | 725 | 79661126 |
Sinus pain | 33.26 | 10.20 | 29 | 82508 | 3713 | 79658138 |
Therapy non-responder | 33.20 | 10.20 | 28 | 82509 | 92277 | 79569574 |
Hepatic failure | 33.11 | 10.20 | 11 | 82526 | 61201 | 79600650 |
Fibromyalgia | 32.92 | 10.20 | 143 | 82394 | 64197 | 79597654 |
Condition aggravated | 32.38 | 10.20 | 347 | 82190 | 500777 | 79161074 |
Sneezing | 31.97 | 10.20 | 66 | 82471 | 19617 | 79642234 |
Poor quality product administered | 31.90 | 10.20 | 28 | 82509 | 3617 | 79658234 |
Incorrect dose administered by product | 31.88 | 10.20 | 11 | 82526 | 209 | 79661642 |
Sinus polyp | 31.70 | 10.20 | 14 | 82523 | 524 | 79661327 |
International normalised ratio increased | 31.34 | 10.20 | 25 | 82512 | 84696 | 79577155 |
Abdominal discomfort | 30.78 | 10.20 | 144 | 82393 | 250583 | 79411268 |
Vomiting | 30.58 | 10.20 | 495 | 82042 | 665333 | 78996518 |
Lung opacity | 30.57 | 10.20 | 32 | 82505 | 5142 | 79656709 |
Skin plaque | 30.44 | 10.20 | 46 | 82491 | 10699 | 79651152 |
Arthropathy | 30.06 | 10.20 | 89 | 82448 | 177022 | 79484829 |
Delirium | 30.04 | 10.20 | 26 | 82511 | 84601 | 79577250 |
Anxiety | 29.24 | 10.20 | 389 | 82148 | 248123 | 79413728 |
Gastrointestinal haemorrhage | 29.04 | 10.20 | 69 | 82468 | 147650 | 79514201 |
Hypomania | 28.38 | 10.20 | 37 | 82500 | 7507 | 79654344 |
Electrocardiogram QT prolonged | 28.34 | 10.20 | 31 | 82506 | 90355 | 79571496 |
Folliculitis | 28.17 | 10.20 | 11 | 82526 | 55369 | 79606482 |
Animal scratch | 27.95 | 10.20 | 18 | 82519 | 1456 | 79660395 |
Exostosis | 27.94 | 10.20 | 57 | 82480 | 16801 | 79645050 |
Dehydration | 27.90 | 10.20 | 147 | 82390 | 248040 | 79413811 |
Drug resistance | 27.86 | 10.20 | 5 | 82532 | 42208 | 79619643 |
Muscle injury | 27.57 | 10.20 | 8 | 82529 | 48553 | 79613298 |
Paranasal sinus discomfort | 27.11 | 10.20 | 28 | 82509 | 4428 | 79657423 |
Feeling cold | 26.97 | 10.20 | 78 | 82459 | 28651 | 79633200 |
Product odour abnormal | 26.95 | 10.20 | 17 | 82520 | 1327 | 79660524 |
Swelling | 26.87 | 10.20 | 124 | 82413 | 216587 | 79445264 |
Respiratory arrest | 26.79 | 10.20 | 13 | 82524 | 57537 | 79604314 |
Impaired healing | 26.46 | 10.20 | 31 | 82506 | 87624 | 79574227 |
Cytomegalovirus infection | 26.17 | 10.20 | 6 | 82531 | 42638 | 79619213 |
Dry skin | 26.01 | 10.20 | 139 | 82398 | 67856 | 79593995 |
Lung perforation | 25.92 | 10.20 | 8 | 82529 | 105 | 79661746 |
Ascites | 25.87 | 10.20 | 24 | 82513 | 75538 | 79586313 |
CFTR gene mutation | 25.85 | 10.20 | 8 | 82529 | 106 | 79661745 |
Sinus congestion | 25.85 | 10.20 | 61 | 82476 | 19835 | 79642016 |
Diarrhoea | 25.61 | 10.20 | 705 | 81832 | 879784 | 78782067 |
Cardiogenic shock | 25.52 | 10.20 | 6 | 82531 | 41908 | 79619943 |
Neutrophil count decreased | 25.50 | 10.20 | 36 | 82501 | 93923 | 79567928 |
Coma | 25.46 | 10.20 | 185 | 82352 | 100464 | 79561387 |
Suicide attempt | 25.39 | 10.20 | 29 | 82508 | 82903 | 79578948 |
Product administered to patient of inappropriate age | 25.32 | 10.20 | 30 | 82507 | 5523 | 79656328 |
Drug reaction with eosinophilia and systemic symptoms | 24.99 | 10.20 | 18 | 82519 | 64226 | 79597625 |
Malignant neoplasm progression | 24.80 | 10.20 | 66 | 82471 | 135924 | 79525927 |
Cystic fibrosis | 24.73 | 10.20 | 25 | 82512 | 3855 | 79657996 |
Ear congestion | 24.70 | 10.20 | 22 | 82515 | 2897 | 79658954 |
Intentional product use issue | 24.70 | 10.20 | 78 | 82459 | 152034 | 79509817 |
Skin burning sensation | 24.56 | 10.20 | 47 | 82490 | 13225 | 79648626 |
Bronchial wall thickening | 24.55 | 10.20 | 21 | 82516 | 2620 | 79659231 |
Hypomagnesaemia | 24.39 | 10.20 | 9 | 82528 | 46902 | 79614949 |
White blood cell count decreased | 24.38 | 10.20 | 106 | 82431 | 188182 | 79473669 |
Croup infectious | 24.32 | 10.20 | 13 | 82524 | 743 | 79661108 |
Skin fragility | 24.29 | 10.20 | 14 | 82523 | 927 | 79660924 |
Toxic epidermal necrolysis | 24.13 | 10.20 | 8 | 82529 | 44573 | 79617278 |
Myelosuppression | 24.08 | 10.20 | 6 | 82531 | 40290 | 79621561 |
Diaphragmatic rupture | 23.89 | 10.20 | 9 | 82528 | 222 | 79661629 |
Exposure to allergen | 23.79 | 10.20 | 10 | 82527 | 331 | 79661520 |
Skin lesion | 23.74 | 10.20 | 96 | 82441 | 41748 | 79620103 |
Growth retardation | 23.46 | 10.20 | 18 | 82519 | 1925 | 79659926 |
Neurotoxicity | 23.41 | 10.20 | 3 | 82534 | 32515 | 79629336 |
Migraine | 23.40 | 10.20 | 163 | 82374 | 87330 | 79574521 |
Chest injury | 23.36 | 10.20 | 21 | 82516 | 2800 | 79659051 |
Upper respiratory tract infection | 23.30 | 10.20 | 168 | 82369 | 91000 | 79570851 |
Shock | 23.25 | 10.20 | 8 | 82529 | 43540 | 79618311 |
Deformity | 22.90 | 10.20 | 38 | 82499 | 9567 | 79652284 |
Rhabdomyolysis | 22.90 | 10.20 | 45 | 82492 | 103086 | 79558765 |
Hospitalisation | 22.58 | 10.20 | 171 | 82366 | 94065 | 79567786 |
Haemoglobin decreased | 22.55 | 10.20 | 136 | 82401 | 221983 | 79439868 |
Perfume sensitivity | 22.48 | 10.20 | 13 | 82524 | 866 | 79660985 |
Jaundice cholestatic | 22.17 | 10.20 | 41 | 82496 | 11243 | 79650608 |
Disseminated intravascular coagulation | 22.08 | 10.20 | 5 | 82532 | 35837 | 79626014 |
Type 2 diabetes mellitus | 22.00 | 10.20 | 117 | 82420 | 57005 | 79604846 |
Blood calcium increased | 21.98 | 10.20 | 39 | 82498 | 10361 | 79651490 |
Cardiac failure | 21.39 | 10.20 | 85 | 82452 | 154757 | 79507094 |
Therapeutic product effect decreased | 21.37 | 10.20 | 92 | 82445 | 163771 | 79498080 |
Depressed mood | 21.27 | 10.20 | 103 | 82434 | 48377 | 79613474 |
Illness | 21.26 | 10.20 | 100 | 82437 | 46411 | 79615440 |
Adiposis dolorosa | 21.24 | 10.20 | 9 | 82528 | 304 | 79661547 |
Product availability issue | 20.83 | 10.20 | 23 | 82514 | 3924 | 79657927 |
Central obesity | 20.58 | 10.20 | 16 | 82521 | 1745 | 79660106 |
Red blood cell sedimentation rate increased | 20.46 | 10.20 | 11 | 82526 | 45931 | 79615920 |
Hepatocellular injury | 20.32 | 10.20 | 12 | 82525 | 47581 | 79614270 |
Alopecia | 20.30 | 10.20 | 148 | 82389 | 231207 | 79430644 |
Altered state of consciousness | 20.24 | 10.20 | 10 | 82527 | 43812 | 79618039 |
Oral candidiasis | 20.13 | 10.20 | 72 | 82465 | 29556 | 79632295 |
Hip arthroplasty | 20.10 | 10.20 | 6 | 82531 | 35750 | 79626101 |
Temperature intolerance | 20.00 | 10.20 | 36 | 82501 | 9669 | 79652182 |
Hypokalaemia | 19.94 | 10.20 | 79 | 82458 | 143961 | 79517890 |
Skin atrophy | 19.90 | 10.20 | 27 | 82510 | 5691 | 79656160 |
Irritable bowel syndrome | 19.89 | 10.20 | 21 | 82516 | 62220 | 79599631 |
Cognitive disorder | 19.77 | 10.20 | 26 | 82511 | 69900 | 79591951 |
Blood potassium increased | 19.77 | 10.20 | 71 | 82466 | 29204 | 79632647 |
Nasal dryness | 19.74 | 10.20 | 24 | 82513 | 4539 | 79657312 |
Respiratory tract infection | 19.63 | 10.20 | 101 | 82436 | 48588 | 79613263 |
Pyrexia | 19.55 | 10.20 | 544 | 81993 | 678165 | 78983686 |
Acquired haemophilia | 19.43 | 10.20 | 16 | 82521 | 1895 | 79659956 |
Liver injury | 19.36 | 10.20 | 18 | 82519 | 56596 | 79605255 |
Oropharyngeal discomfort | 19.34 | 10.20 | 30 | 82507 | 7136 | 79654715 |
Exposure during pregnancy | 19.27 | 10.20 | 48 | 82489 | 101084 | 79560767 |
Lacrimation increased | 19.18 | 10.20 | 59 | 82478 | 22418 | 79639433 |
Maple syrup disease | 19.11 | 10.20 | 4 | 82533 | 8 | 79661843 |
Depressed level of consciousness | 19.11 | 10.20 | 45 | 82492 | 96607 | 79565244 |
Adjustment disorder | 18.89 | 10.20 | 22 | 82515 | 3978 | 79657873 |
Ureteral disorder | 18.84 | 10.20 | 10 | 82527 | 563 | 79661288 |
Stress | 18.81 | 10.20 | 144 | 82393 | 79468 | 79582383 |
Tubulointerstitial nephritis | 18.79 | 10.20 | 8 | 82529 | 38227 | 79623624 |
Skin wrinkling | 18.52 | 10.20 | 13 | 82524 | 1213 | 79660638 |
Device dislocation | 18.41 | 10.20 | 64 | 82473 | 25906 | 79635945 |
Drug level increased | 18.39 | 10.20 | 9 | 82528 | 39642 | 79622209 |
Adrenal insufficiency | 18.32 | 10.20 | 68 | 82469 | 28419 | 79633432 |
Hereditary angioedema | 18.28 | 10.20 | 25 | 82512 | 5310 | 79656541 |
Flail chest | 18.18 | 10.20 | 6 | 82531 | 99 | 79661752 |
Cockroach allergy | 18.07 | 10.20 | 6 | 82531 | 101 | 79661750 |
Decreased appetite | 17.94 | 10.20 | 248 | 82289 | 342170 | 79319681 |
Acute myeloid leukaemia | 17.70 | 10.20 | 5 | 82532 | 30880 | 79630971 |
Blood immunoglobulin E decreased | 17.69 | 10.20 | 6 | 82531 | 108 | 79661743 |
Cerebral infarction | 17.50 | 10.20 | 13 | 82524 | 45663 | 79616188 |
Panic attack | 17.45 | 10.20 | 60 | 82477 | 24156 | 79637695 |
Cholestasis | 17.32 | 10.20 | 17 | 82520 | 52092 | 79609759 |
Drug-induced liver injury | 17.28 | 10.20 | 26 | 82511 | 66091 | 79595760 |
Epistaxis | 17.26 | 10.20 | 184 | 82353 | 111331 | 79550520 |
Bronchial irritation | 17.09 | 10.20 | 5 | 82532 | 54 | 79661797 |
Erythema marginatum | 17.08 | 10.20 | 4 | 82533 | 16 | 79661835 |
Neoplasm progression | 17.01 | 10.20 | 17 | 82520 | 51665 | 79610186 |
Hypoacusis | 16.97 | 10.20 | 69 | 82468 | 30081 | 79631770 |
Purpura senile | 16.73 | 10.20 | 9 | 82528 | 521 | 79661330 |
Polymyalgia rheumatica | 16.67 | 10.20 | 22 | 82515 | 4515 | 79657336 |
Allergy to animal | 16.66 | 10.20 | 13 | 82524 | 1426 | 79660425 |
Bladder pain | 16.65 | 10.20 | 16 | 82521 | 2321 | 79659530 |
Tarsal tunnel syndrome | 16.63 | 10.20 | 9 | 82528 | 527 | 79661324 |
Dystrophic calcification | 16.53 | 10.20 | 6 | 82531 | 133 | 79661718 |
Increased upper airway secretion | 16.52 | 10.20 | 21 | 82516 | 4156 | 79657695 |
Hypersomnia | 16.46 | 10.20 | 57 | 82480 | 23029 | 79638822 |
Pulmonary eosinophilia | 16.45 | 10.20 | 10 | 82527 | 731 | 79661120 |
Dry throat | 16.41 | 10.20 | 29 | 82508 | 7677 | 79654174 |
Procedural anxiety | 16.14 | 10.20 | 10 | 82527 | 756 | 79661095 |
Tongue pruritus | 16.12 | 10.20 | 9 | 82528 | 561 | 79661290 |
Hyperbilirubinaemia | 15.97 | 10.20 | 3 | 82534 | 24515 | 79637336 |
Haemoptysis | 15.97 | 10.20 | 106 | 82431 | 55893 | 79605958 |
Genital rash | 15.76 | 10.20 | 11 | 82526 | 1017 | 79660834 |
Orthostatic hypotension | 15.76 | 10.20 | 21 | 82516 | 56143 | 79605708 |
Aortic aneurysm | 15.74 | 10.20 | 30 | 82507 | 8416 | 79653435 |
Respiratory failure | 15.73 | 10.20 | 116 | 82421 | 180795 | 79481056 |
Papillary renal cell carcinoma | 15.70 | 10.20 | 7 | 82530 | 268 | 79661583 |
Eosinophil count increased | 15.63 | 10.20 | 46 | 82491 | 17059 | 79644792 |
Expired product administered | 15.62 | 10.20 | 27 | 82510 | 7024 | 79654827 |
Blood pressure increased | 15.50 | 10.20 | 306 | 82231 | 211054 | 79450797 |
Tumour lysis syndrome | 15.45 | 10.20 | 3 | 82534 | 23936 | 79637915 |
Chorioretinopathy | 15.38 | 10.20 | 15 | 82522 | 2216 | 79659635 |
Acute hepatic failure | 15.29 | 10.20 | 6 | 82531 | 30107 | 79631744 |
Burns third degree | 15.03 | 10.20 | 8 | 82529 | 453 | 79661398 |
Sedation | 14.98 | 10.20 | 19 | 82518 | 51876 | 79609975 |
Skin exfoliation | 14.93 | 10.20 | 103 | 82434 | 54997 | 79606854 |
Osteoarthritis | 14.91 | 10.20 | 147 | 82390 | 87162 | 79574689 |
Psoriatic arthropathy | 14.88 | 10.20 | 37 | 82500 | 77962 | 79583889 |
Depressive symptom | 14.76 | 10.20 | 25 | 82512 | 6398 | 79655453 |
Lower respiratory tract infection | 14.65 | 10.20 | 201 | 82336 | 129019 | 79532832 |
Cholelithiasis | 14.60 | 10.20 | 99 | 82438 | 52565 | 79609286 |
Tachyarrhythmia | 14.57 | 10.20 | 26 | 82511 | 6936 | 79654915 |
Ear pain | 14.54 | 10.20 | 70 | 82467 | 32799 | 79629052 |
Hepatic enzyme increased | 14.52 | 10.20 | 120 | 82417 | 182490 | 79479361 |
Fall | 14.49 | 10.20 | 389 | 82148 | 487240 | 79174611 |
Renal tubular necrosis | 14.45 | 10.20 | 4 | 82533 | 25035 | 79636816 |
Neutropenic sepsis | 14.40 | 10.20 | 5 | 82532 | 27059 | 79634792 |
Hypothalamic pituitary adrenal axis suppression | 14.38 | 10.20 | 7 | 82530 | 328 | 79661523 |
Secretion discharge | 14.31 | 10.20 | 41 | 82496 | 14981 | 79646870 |
Ear infection | 14.28 | 10.20 | 72 | 82465 | 34360 | 79627491 |
Circulatory collapse | 14.07 | 10.20 | 11 | 82526 | 37657 | 79624194 |
Myalgia | 14.03 | 10.20 | 270 | 82267 | 185371 | 79476480 |
Fungal disease carrier | 13.98 | 10.20 | 7 | 82530 | 349 | 79661502 |
Insomnia | 13.87 | 10.20 | 342 | 82195 | 244828 | 79417023 |
Cushing's syndrome | 13.76 | 10.20 | 10 | 82527 | 985 | 79660866 |
Thoracic operation | 13.68 | 10.20 | 6 | 82531 | 221 | 79661630 |
Blood immunoglobulin E increased | 13.66 | 10.20 | 23 | 82514 | 5859 | 79655992 |
Haematochezia | 13.49 | 10.20 | 46 | 82491 | 87599 | 79574252 |
Obstruction | 13.44 | 10.20 | 20 | 82517 | 4590 | 79657261 |
Breast conserving surgery | 13.41 | 10.20 | 9 | 82528 | 781 | 79661070 |
Enthesopathy | 13.39 | 10.20 | 34 | 82503 | 11574 | 79650277 |
Knee arthroplasty | 13.37 | 10.20 | 15 | 82522 | 43233 | 79618618 |
Pneumonia | 13.32 | 10.20 | 822 | 81715 | 659424 | 79002427 |
Sitting disability | 13.26 | 10.20 | 7 | 82530 | 390 | 79661461 |
Respiratory depression | 13.23 | 10.20 | 6 | 82531 | 27624 | 79634227 |
Rash macular | 13.11 | 10.20 | 62 | 82475 | 28837 | 79633014 |
Forced expiratory volume abnormal | 13.10 | 10.20 | 5 | 82532 | 128 | 79661723 |
Prescribed overdose | 13.01 | 10.20 | 12 | 82525 | 37871 | 79623980 |
Pulmonary mass | 12.96 | 10.20 | 62 | 82475 | 28972 | 79632879 |
Pruritus | 12.89 | 10.20 | 515 | 82022 | 394133 | 79267718 |
Cytokine release syndrome | 12.84 | 10.20 | 11 | 82526 | 35987 | 79625864 |
Hepatic cytolysis | 12.84 | 10.20 | 6 | 82531 | 27145 | 79634706 |
Exposure to fungus | 12.82 | 10.20 | 5 | 82532 | 136 | 79661715 |
Body temperature abnormal | 12.81 | 10.20 | 14 | 82523 | 2361 | 79659490 |
Hypertension | 12.76 | 10.20 | 440 | 82097 | 330552 | 79331299 |
Intentional self-injury | 12.71 | 10.20 | 9 | 82528 | 32410 | 79629441 |
Allergic sinusitis | 12.65 | 10.20 | 9 | 82528 | 858 | 79660993 |
Appetite disorder | 12.62 | 10.20 | 26 | 82511 | 7713 | 79654138 |
Ear disorder | 12.62 | 10.20 | 18 | 82519 | 3975 | 79657876 |
Product quality control issue | 12.62 | 10.20 | 3 | 82534 | 13 | 79661838 |
Hearing disability | 12.59 | 10.20 | 4 | 82533 | 58 | 79661793 |
Post-traumatic stress disorder | 12.57 | 10.20 | 20 | 82517 | 4861 | 79656990 |
Hypothermia | 12.46 | 10.20 | 4 | 82533 | 22742 | 79639109 |
Multiple allergies | 12.44 | 10.20 | 31 | 82506 | 10429 | 79651422 |
Telangiectasia | 12.42 | 10.20 | 11 | 82526 | 1438 | 79660413 |
Tongue dry | 12.38 | 10.20 | 10 | 82527 | 1152 | 79660699 |
Pharyngeal oedema | 12.32 | 10.20 | 41 | 82496 | 16231 | 79645620 |
Urosepsis | 12.31 | 10.20 | 6 | 82531 | 26489 | 79635362 |
Primary familial brain calcification | 12.26 | 10.20 | 3 | 82534 | 15 | 79661836 |
Breath sounds absent | 12.23 | 10.20 | 6 | 82531 | 286 | 79661565 |
Subarachnoid haemorrhage | 12.21 | 10.20 | 5 | 82532 | 24460 | 79637391 |
Plasma cell myeloma | 12.03 | 10.20 | 23 | 82514 | 53236 | 79608615 |
Increased bronchial secretion | 12.02 | 10.20 | 16 | 82521 | 3311 | 79658540 |
Inflammation | 11.99 | 10.20 | 53 | 82484 | 93700 | 79568151 |
Eosinophilic bronchitis | 11.86 | 10.20 | 7 | 82530 | 485 | 79661366 |
Peritoneal perforation | 11.74 | 10.20 | 5 | 82532 | 171 | 79661680 |
Grip strength decreased | 11.70 | 10.20 | 4 | 82533 | 21865 | 79639986 |
Aphonia | 11.68 | 10.20 | 30 | 82507 | 10282 | 79651569 |
Coagulopathy | 11.67 | 10.20 | 12 | 82525 | 35994 | 79625857 |
Seizure | 11.66 | 10.20 | 132 | 82405 | 188702 | 79473149 |
Inguinal hernia repair | 11.54 | 10.20 | 6 | 82531 | 324 | 79661527 |
Pancreatitis relapsing | 11.53 | 10.20 | 9 | 82528 | 987 | 79660864 |
Mesenteric haemorrhage | 11.50 | 10.20 | 4 | 82533 | 78 | 79661773 |
Diabetic ketoacidosis | 11.49 | 10.20 | 11 | 82526 | 34111 | 79627740 |
Lung neoplasm malignant | 11.44 | 10.20 | 58 | 82479 | 27734 | 79634117 |
Eye swelling | 11.44 | 10.20 | 56 | 82481 | 26412 | 79635439 |
Eosinophil count abnormal | 11.43 | 10.20 | 8 | 82529 | 743 | 79661108 |
Throat tightness | 11.32 | 10.20 | 58 | 82479 | 27849 | 79634002 |
Lymphopenia | 11.32 | 10.20 | 9 | 82528 | 30548 | 79631303 |
Brain oedema | 11.32 | 10.20 | 6 | 82531 | 25257 | 79636594 |
Social fear | 11.29 | 10.20 | 3 | 82534 | 22 | 79661829 |
Lung diffusion disorder | 11.23 | 10.20 | 5 | 82532 | 191 | 79661660 |
Hot flush | 11.19 | 10.20 | 96 | 82441 | 54781 | 79607070 |
Blister | 11.17 | 10.20 | 75 | 82462 | 119401 | 79542450 |
Cardiac failure congestive | 11.13 | 10.20 | 94 | 82443 | 142308 | 79519543 |
Ventricular fibrillation | 11.10 | 10.20 | 10 | 82527 | 31916 | 79629935 |
Aspartate aminotransferase increased | 11.07 | 10.20 | 91 | 82446 | 138550 | 79523301 |
Heart rate increased | 11.04 | 10.20 | 181 | 82356 | 120543 | 79541308 |
Bronchospasm | 11.04 | 10.20 | 53 | 82484 | 24806 | 79637045 |
Nasal polypectomy | 10.95 | 10.20 | 3 | 82534 | 25 | 79661826 |
Wrist fracture | 10.84 | 10.20 | 32 | 82505 | 11889 | 79649962 |
Bone hypertrophy | 10.83 | 10.20 | 7 | 82530 | 570 | 79661281 |
Conjunctivitis | 10.82 | 10.20 | 54 | 82483 | 25661 | 79636190 |
Product deposit | 10.78 | 10.20 | 7 | 82530 | 574 | 79661277 |
Vestibular disorder | 10.76 | 10.20 | 13 | 82524 | 2442 | 79659409 |
Calculus urinary | 10.74 | 10.20 | 13 | 82524 | 2447 | 79659404 |
Lichenification | 10.68 | 10.20 | 8 | 82529 | 825 | 79661026 |
Menopause | 10.67 | 10.20 | 12 | 82525 | 2090 | 79659761 |
Diaphragmatic paralysis | 10.66 | 10.20 | 9 | 82528 | 1103 | 79660748 |
Progressive multifocal leukoencephalopathy | 10.63 | 10.20 | 4 | 82533 | 20596 | 79641255 |
Dermatitis allergic | 10.61 | 10.20 | 42 | 82495 | 18088 | 79643763 |
Bronchiolitis | 10.57 | 10.20 | 17 | 82520 | 4171 | 79657680 |
Serotonin syndrome | 10.56 | 10.20 | 19 | 82518 | 45008 | 79616843 |
Stomatitis | 10.53 | 10.20 | 99 | 82438 | 146658 | 79515193 |
Liver disorder | 10.48 | 10.20 | 39 | 82498 | 72378 | 79589473 |
Basal cell carcinoma | 10.46 | 10.20 | 14 | 82523 | 37361 | 79624490 |
Hepatic encephalopathy | 10.45 | 10.20 | 6 | 82531 | 24160 | 79637691 |
Hypoglycaemia | 10.41 | 10.20 | 62 | 82475 | 101532 | 79560319 |
Mental status changes | 10.40 | 10.20 | 35 | 82502 | 66924 | 79594927 |
Pneumocystis jirovecii pneumonia | 10.35 | 10.20 | 11 | 82526 | 32497 | 79629354 |
Wound secretion | 10.34 | 10.20 | 21 | 82516 | 6167 | 79655684 |
Intentional product misuse | 10.33 | 10.20 | 57 | 82480 | 95108 | 79566743 |
Accident | 10.32 | 10.20 | 26 | 82511 | 8805 | 79653046 |
Obesity | 10.32 | 10.20 | 67 | 82470 | 35058 | 79626793 |
Haemodialysis | 10.30 | 10.20 | 3 | 82534 | 18165 | 79643686 |
Haemorrhage | 10.21 | 10.20 | 54 | 82483 | 91064 | 79570787 |
None
Source | Code | Description |
---|---|---|
ATC | D07AC13 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, PLAIN Corticosteroids, potent (group III) |
ATC | D07XC03 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, OTHER COMBINATIONS Corticosteroids, potent, other combinations |
ATC | R01AD09 | RESPIRATORY SYSTEM NASAL PREPARATIONS DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE Corticosteroids |
ATC | R01AD59 | RESPIRATORY SYSTEM NASAL PREPARATIONS DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE Corticosteroids |
ATC | R03AK09 | RESPIRATORY SYSTEM DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES ADRENERGICS, INHALANTS Adrenergics in combination with corticosteroids or other drugs, excl. anticholinergics |
ATC | R03AK14 | RESPIRATORY SYSTEM DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES ADRENERGICS, INHALANTS Adrenergics in combination with corticosteroids or other drugs, excl. anticholinergics |
ATC | R03AL12 | RESPIRATORY SYSTEM DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES ADRENERGICS, INHALANTS Adrenergics in combination with anticholinergics incl. triple combinations with corticosteroids |
ATC | R03BA07 | RESPIRATORY SYSTEM DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS Glucocorticoids |
FDA MoA | N0000175450 | Corticosteroid Hormone Receptor Agonists |
FDA EPC | N0000175576 | Corticosteroid |
MeSH PA | D018926 | Anti-Allergic Agents |
MeSH PA | D000893 | Anti-Inflammatory Agents |
MeSH PA | D003879 | Dermatologic Agents |
CHEBI has role | CHEBI:35472 | anti-inflammatory drugs |
CHEBI has role | CHEBI:50177 | dermatologic agent |
CHEBI has role | CHEBI:50857 | anti-allergic drugs |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Atopic dermatitis | indication | 24079001 | DOID:3310 |
Contact dermatitis | indication | 40275004 | DOID:2773 |
Seborrheic dermatitis | indication | 50563003 | DOID:8741 |
Lichen simplex chronicus | indication | 53891004 | |
Allergic rhinitis | indication | 61582004 | |
Granuloma annulare | indication | 65508009 | DOID:3777 |
Pruritus ani | indication | 90446007 | |
Asthma | indication | 195967001 | DOID:2841 |
Discoid lupus erythematosus | indication | 200938002 | |
Plaque psoriasis | indication | 200965009 | |
Scalp psoriasis | indication | 238608008 | |
Non-allergic asthma | indication | 266361008 | DOID:9360 |
Pruritus of genital organs | indication | 267802000 | |
Eruption of skin | indication | 271807003 | DOID:0050486 |
Allergic asthma | indication | 389145006 | DOID:9415 |
Primary cutaneous T-cell lymphoma | indication | 400122007 | |
Asthma management | indication | 406162001 | |
Allergic Rhinitis Prevention | indication | ||
Chronic Non-Allergic Rhinitis | indication | ||
Severe chronic obstructive pulmonary disease | off-label use | 313299006 | |
Mycosis | contraindication | 3218000 | DOID:1564 |
Ocular hypertension | contraindication | 4210003 | DOID:9282 |
Inactive tuberculosis | contraindication | 11999007 | |
Epistaxis | contraindication | 12441001 | |
Asthenia | contraindication | 13791008 | |
Measles | contraindication | 14189004 | DOID:8622 |
Disease caused by parasite | contraindication | 17322007 | |
Glaucoma | contraindication | 23986001 | DOID:1686 |
Acute tuberculosis | contraindication | 25629007 | |
Immunosuppression | contraindication | 38013005 | |
Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
Varicella | contraindication | 38907003 | DOID:8659 |
Hypokalemia | contraindication | 43339004 | |
Conduction disorder of the heart | contraindication | 44808001 | |
Skin ulcer | contraindication | 46742003 | |
Osteoporosis | contraindication | 64859006 | DOID:11476 |
Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
Hypopituitarism | contraindication | 74728003 | DOID:9406 |
Perforation of nasal septum | contraindication | 80142000 | |
Bacterial infectious disease | contraindication | 87628006 | |
Operation on nose | contraindication | 88733004 | |
Thyrotoxicosis | contraindication | 90739004 | DOID:7997 |
Fissure in skin | contraindication | 95321009 | |
Bilateral cataracts | contraindication | 95722004 | |
Prolonged QT interval | contraindication | 111975006 | |
Seizure disorder | contraindication | 128613002 | |
Ophthalmic herpes simplex | contraindication | 186542001 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Telangiectasia disorder | contraindication | 247479008 | |
Exacerbation of asthma | contraindication | 281239006 | |
Varicella-zoster virus infection | contraindication | 309465005 | |
Osteopenia | contraindication | 312894000 | |
Skin irritation | contraindication | 367466007 | |
Adrenal cortical hypofunction | contraindication | 386584007 | DOID:10493 |
Atrophoderma | contraindication | 399979006 | |
Peripheral vascular disease | contraindication | 400047006 | |
Chronic myocardial ischemia | contraindication | 413844008 | DOID:3393 |
Denuded skin | contraindication | 418242004 | |
Congenital long QT syndrome | contraindication | 442917000 | |
Nasal Septal Ulcers | contraindication | ||
Untreated Fungal Infection | contraindication | ||
Nasal Trauma | contraindication | ||
Nasal Candidiasis | contraindication | ||
Uncontrolled Bacterial Infections | contraindication |
Species | Use | Relation |
---|---|---|
Dogs | Otitis externa | Indication |
Product | Applicant | Ingredients |
---|---|---|
Mometamax Otic Suspension | Intervet Inc. | 3 |
Posatex Otic Suspension | Intervet Inc. | 3 |
CLARO | Elanco US Inc. | 3 |
Mometavet | Med-Pharmex Inc. | 3 |
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 12.01 | acidic |
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
---|---|---|---|---|---|---|---|---|---|---|
1.35MG | SINUVA | INTERSECT ENT INC | N209310 | Dec. 8, 2017 | RX | IMPLANT | IMPLANTATION | 7662141 | March 12, 2024 | TREATMENT OF NASAL POLYPS IN PATIENTS >=18 YEARS OF AGE WHO HAVE HAD ETHMOID SINUS SURGERY USING A CORTICOSTEROID-ELUTING (MOMETASONE FUROATE) IMPLANT |
1.35MG | SINUVA | INTERSECT ENT INC | N209310 | Dec. 8, 2017 | RX | IMPLANT | IMPLANTATION | 7713255 | March 12, 2024 | TREATMENT OF NASAL POLYPS IN PATIENTS >=18 YEARS OF AGE WHO HAVE HAD ETHMOID SINUS SURGERY USING A CORTICOSTEROID-ELUTING (MOMETASONE FUROATE) IMPLANT |
1.35MG | SINUVA | INTERSECT ENT INC | N209310 | Dec. 8, 2017 | RX | IMPLANT | IMPLANTATION | 7951130 | March 12, 2024 | TREATMENT OF NASAL POLYPS IN PATIENTS >=18 YEARS OF AGE WHO HAVE HAD ETHMOID SINUS SURGERY USING A CORTICOSTEROID-ELUTING (MOMETASONE FUROATE) IMPLANT |
1.35MG | SINUVA | INTERSECT ENT INC | N209310 | Dec. 8, 2017 | RX | IMPLANT | IMPLANTATION | 7951131 | March 12, 2024 | TREATMENT OF NASAL POLYPS IN PATIENTS >=18 YEARS OF AGE WHO HAVE HAD ETHMOID SINUS SURGERY USING A CORTICOSTEROID-ELUTING (MOMETASONE FUROATE) IMPLANT |
1.35MG | SINUVA | INTERSECT ENT INC | N209310 | Dec. 8, 2017 | RX | IMPLANT | IMPLANTATION | 7951133 | March 12, 2024 | TREATMENT OF NASAL POLYPS IN PATIENTS >=18 YEARS OF AGE WHO HAVE HAD ETHMOID SINUS SURGERY USING A CORTICOSTEROID-ELUTING (MOMETASONE FUROATE) IMPLANT |
1.35MG | SINUVA | INTERSECT ENT INC | N209310 | Dec. 8, 2017 | RX | IMPLANT | IMPLANTATION | 8109918 | March 12, 2024 | TREATMENT OF NASAL POLYPS IN PATIENTS >=18 YEARS OF AGE WHO HAVE HAD ETHMOID SINUS SURGERY USING A CORTICOSTEROID-ELUTING (MOMETASONE FUROATE) IMPLANT |
1.35MG | SINUVA | INTERSECT ENT INC | N209310 | Dec. 8, 2017 | RX | IMPLANT | IMPLANTATION | 9585681 | April 4, 2026 | TREATMENT OF NASAL POLYPS IN PATIENTS >=18 YEARS OF AGE WHO HAVE HAD ETHMOID SINUS SURGERY USING A CORTICOSTEROID-ELUTING (MOMETASONE FUROATE) IMPLANT |
1.35MG | SINUVA | INTERSECT ENT INC | N209310 | Dec. 8, 2017 | RX | IMPLANT | IMPLANTATION | 7544192 | Nov. 29, 2026 | TREATMENT OF NASAL POLYPS IN PATIENTS >=18 YEARS OF AGE WHO HAVE HAD ETHMOID SINUS SURGERY USING A CORTICOSTEROID-ELUTING (MOMETASONE FUROATE) IMPLANT |
1.35MG | SINUVA | INTERSECT ENT INC | N209310 | Dec. 8, 2017 | RX | IMPLANT | IMPLANTATION | 8025635 | June 12, 2027 | TREATMENT OF NASAL POLYPS IN PATIENTS >=18 YEARS OF AGE WHO HAVE HAD ETHMOID SINUS SURGERY USING A CORTICOSTEROID-ELUTING (MOMETASONE FUROATE) IMPLANT |
1.35MG | SINUVA | INTERSECT ENT INC | N209310 | Dec. 8, 2017 | RX | IMPLANT | IMPLANTATION | 10357640 | Oct. 3, 2031 | TREATMENT OF NASAL POLYPS IN PATIENTS >=18 YEARS OF AGE WHO HAVE HAD ETHMOID SINUS SURGERY USING A CORTICOSTEROID-ELUTING (MOMETASONE FUROATE) IMPLANT |
0.025MG/SPRAY;0.665MG/SPRAY | RYALTRIS | GLENMARK SPECIALTY | N211746 | Jan. 13, 2022 | RX | SPRAY, METERED | NASAL | 10016443 | Sept. 4, 2034 | TREATMENT OF SEASONAL ALLERGIC RHINITIS BY NASALY ADMINISTERING A COMBINATION OF OLOPATADINE HYDROCHLORIDE AND MOMETASONE FUROATE |
0.025MG/SPRAY;0.665MG/SPRAY | RYALTRIS | GLENMARK SPECIALTY | N211746 | Jan. 13, 2022 | RX | SPRAY, METERED | NASAL | 10517880 | Sept. 4, 2034 | TREATMENT OF SEASONAL ALLERGIC RHINITIS BY NASALY ADMINISTERING A COMBINATION OF OLOPATADINE HYDROCHLORIDE AND MOMETASONE FUROATE |
0.025MG/SPRAY;0.665MG/SPRAY | RYALTRIS | GLENMARK SPECIALTY | N211746 | Jan. 13, 2022 | RX | SPRAY, METERED | NASAL | 10548907 | Sept. 4, 2034 | TREATMENT OF SEASONAL ALLERGIC RHINITIS BY NASALY ADMINISTERING A COMBINATION OF OLOPATADINE HYDROCHLORIDE AND MOMETASONE FUROATE |
0.025MG/SPRAY;0.665MG/SPRAY | RYALTRIS | GLENMARK SPECIALTY | N211746 | Jan. 13, 2022 | RX | SPRAY, METERED | NASAL | 10646500 | Sept. 4, 2034 | TREATMENT OF SEASONAL ALLERGIC RHINITIS BY NASALY ADMINISTERING A COMBINATION OF OLOPATADINE HYDROCHLORIDE AND MOMETASONE FUROATE |
0.025MG/SPRAY;0.665MG/SPRAY | RYALTRIS | GLENMARK SPECIALTY | N211746 | Jan. 13, 2022 | RX | SPRAY, METERED | NASAL | 10758550 | Sept. 4, 2034 | TREATMENT OF SEASONAL ALLERGIC RHINITIS BY NASALY ADMINISTERING A COMBINATION OF OLOPATADINE HYDROCHLORIDE AND MOMETASONE FUROATE TO A PEDIATRIC PATIENT |
0.025MG/SPRAY;0.665MG/SPRAY | RYALTRIS | GLENMARK SPECIALTY | N211746 | Jan. 13, 2022 | RX | SPRAY, METERED | NASAL | 10765686 | Sept. 4, 2034 | METHOD OF DELIVERING A COMBINATION OF OLOPATADINE HYDROCHLORIDE AND MOMETASONE FUROATE TO A NASAL AIRWAY |
0.025MG/SPRAY;0.665MG/SPRAY | RYALTRIS | GLENMARK SPECIALTY | N211746 | Jan. 13, 2022 | RX | SPRAY, METERED | NASAL | 11400101 | Sept. 4, 2034 | TREATMENT OF SEASONAL ALLERGIC RHINITIS BY NASALY ADMINISTERING A COMBINATION OF OLOPATADINE HYDROCHLORIDE AND MOMETASONE FUROATE |
0.025MG/SPRAY;0.665MG/SPRAY | RYALTRIS | GLENMARK SPECIALTY | N211746 | Jan. 13, 2022 | RX | SPRAY, METERED | NASAL | 9078923 | Sept. 4, 2034 | TREATMENT OF SEASONAL ALLERGIC RHINITIS BY NASALY ADMINISTERING A COMBINATION OF OLOPATADINE HYDROCHLORIDE AND MOMETASONE FUROATE |
0.025MG/SPRAY;0.665MG/SPRAY | RYALTRIS | GLENMARK SPECIALTY | N211746 | Jan. 13, 2022 | RX | SPRAY, METERED | NASAL | 9750754 | Sept. 4, 2034 | TREATMENT OF SEASONAL ALLERGIC RHINITIS BY NASALY ADMINISTERING A COMBINATION OF OLOPATADINE HYDROCHLORIDE AND MOMETASONE FUROATE |
1.35MG | SINUVA | INTERSECT ENT INC | N209310 | Dec. 8, 2017 | RX | IMPLANT | IMPLANTATION | 10232152 | Nov. 24, 2034 | TREATMENT OF NASAL POLYPS IN PATIENTS >=18 YEARS OF AGE WHO HAVE HAD ETHMOID SINUS SURGERY USING A CORTICOSTEROID-ELUTING (MOMETASONE FUROATE) IMPLANT |
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Exclusivity date | Description |
---|---|---|---|---|---|---|---|---|---|
0.005MG/INH;0.05MG/INH | DULERA | ORGANON LLC | N022518 | Aug. 12, 2019 | RX | AEROSOL, METERED | INHALATION | Feb. 12, 2023 | PEDIATRIC EXCLUSIVITY |
0.05MG/INH | ASMANEX HFA | ORGANON LLC | N205641 | Aug. 12, 2019 | RX | AEROSOL, METERED | INHALATION | Feb. 12, 2023 | PEDIATRIC EXCLUSIVITY |
0.025MG/SPRAY;0.665MG/SPRAY | RYALTRIS | GLENMARK SPECIALTY | N211746 | Jan. 13, 2022 | RX | SPRAY, METERED | NASAL | Jan. 13, 2025 | NEW PRODUCT |
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Glucocorticoid receptor | Nuclear hormone receptor | AGONIST | Ki | 9.15 | CHEMBL | CHEMBL | |||
Multidrug resistance protein 1 | Transporter | IC50 | 6.13 | WOMBAT-PK | |||||
Progesterone receptor | Nuclear hormone receptor | EC50 | 9.90 | WOMBAT-PK |
ID | Source |
---|---|
4019844 | VUID |
N0000147931 | NUI |
D00690 | KEGG_DRUG |
4019367 | VANDF |
4019844 | VANDF |
4021125 | VANDF |
C0066700 | UMLSCUI |
CHEBI:47564 | CHEBI |
CHEBI:6970 | CHEBI |
MOF | PDB_CHEM_ID |
CHEMBL1161 | ChEMBL_ID |
D000068656 | MESH_DESCRIPTOR_UI |
DB14512 | DRUGBANK_ID |
141646-00-6 | SECONDARY_CAS_RN |
04201GDN4R | UNII |
441336 | PUBCHEM_CID |
DB00764 | DRUGBANK_ID |
108118 | RXNORM |
11404 | MMSL |
239640 | MMSL |
5129 | MMSL |
5130 | MMSL |
d05262 | MMSL |
002205 | NDDF |
395802006 | SNOMEDCT_US |
395803001 | SNOMEDCT_US |
395990009 | SNOMEDCT_US |
75203002 | SNOMEDCT_US |
C0360564 | UMLSCUI |
6030 | INN_ID |
105102-22-5 | SECONDARY_CAS_RN |
441335 | PUBCHEM_CID |
9029 | IUPHAR_LIGAND_ID |
8HR4QJ6DW8 | UNII |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Dulera | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0085-4610 | AEROSOL | 200 ug | RESPIRATORY (INHALATION) | NDA | 29 sections |
Dulera | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0085-7206 | AEROSOL | 100 ug | RESPIRATORY (INHALATION) | NDA | 29 sections |
Nasonex | HUMAN OTC DRUG LABEL | 1 | 0113-1720 | SPRAY | 50 ug | NASAL | NDA | 17 sections |
Nasonex | HUMAN OTC DRUG LABEL | 1 | 0113-1720 | SPRAY | 50 ug | NASAL | NDA | 17 sections |
Childrens Nasonex | HUMAN OTC DRUG LABEL | 1 | 0113-1999 | SPRAY | 50 ug | NASAL | NDA | 17 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0168-0270 | CREAM | 1 mg | TOPICAL | ANDA | 28 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0168-0271 | OINTMENT | 1 mg | TOPICAL | ANDA | 28 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0168-0272 | SOLUTION | 1 mg | TOPICAL | ANDA | 29 sections |
allergy nasal | HUMAN OTC DRUG LABEL | 1 | 0363-2060 | SPRAY | 50 ug | NASAL | NDA | 17 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0713-0634 | CREAM | 1 mg | TOPICAL | ANDA | 27 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0713-0634 | CREAM | 1 mg | TOPICAL | ANDA | 27 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0713-0635 | OINTMENT | 1 mg | TOPICAL | ANDA | 24 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0713-0701 | SOLUTION | 1 mg | TOPICAL | ANDA | 27 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0713-0701 | SOLUTION | 1 mg | TOPICAL | ANDA | 27 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0713-0726 | CREAM | 1 mg | TOPICAL | ANDA | 27 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0713-0726 | CREAM | 1 mg | TOPICAL | ANDA | 27 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0713-0727 | OINTMENT | 1 mg | TOPICAL | ANDA | 24 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0713-0727 | OINTMENT | 1 mg | TOPICAL | ANDA | 24 sections |
Sinuva | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10599-003 | IMPLANT | 1350 ug | INTRASINAL | NDA | 29 sections |
Sinuva | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10599-003 | IMPLANT | 1350 ug | INTRASINAL | NDA | 29 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-527 | OINTMENT | 1 mg | TOPICAL | ANDA | 26 sections |
MOMETASONE FUROATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16590-993 | CREAM | 1 mg | TOPICAL | ANDA | 10 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16714-974 | CREAM | 1 mg | TOPICAL | ANDA | 27 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 21695-786 | CREAM | 1 mg | TOPICAL | ANDA | 13 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42254-175 | OINTMENT | 1 mg | TOPICAL | ANDA | 13 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 45802-118 | SOLUTION | 1 mg | TOPICAL | ANDA | 27 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 45802-118 | SOLUTION | 1 mg | TOPICAL | ANDA | 27 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 45802-119 | OINTMENT | 1 mg | TOPICAL | ANDA | 29 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 45802-257 | CREAM | 1 mg | TOPICAL | ANDA | 29 sections |
Mometasone Furoate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 45802-257 | CREAM | 1 mg | TOPICAL | ANDA | 29 sections |