amiphenazole indications/contra

Stem definitionDrug idCAS RN
177 490-55-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • amiphenazole
  • amifenazol
  • amifenazole
  • amiphenazol
  • amphisol
  • daftazol
  • daptazile
  • daptazole
  • fenamizol
  • phenamizol
  • phenamizole
used as a respiratory tonic, morphine antagonist, & antidote in barbiturate poisoning; RN given refers to parent cpd; sturcture
  • Molecular weight: 191.25
  • Formula: C9H9N3S
  • CLOGP: 2.07
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 2
  • TPSA: 64.93
  • ALOGS: -2.15
  • ROTB: 1

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
MeSH PA D019141 Respiratory System Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 5.89 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
CHEBI:134843 CHEBI
7ZJ8PWY0XD UNII
510 INN_ID
10275 PUBCHEM_CID
7975001 SNOMEDCT_US
CHEMBL1514085 ChEMBL_ID
C004484 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None