aminorex 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
anorexics 175 2207-50-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • McN-742
  • aminorex
  • aminoxafen
  • aminoxaphen
  • apiquel
An amphetamine-like anorectic agent. It may cause pulmonary hypertension.
  • Molecular weight: 162.19
  • Formula: C9H10N2O
  • CLOGP: 0.92
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 47.61
  • ALOGS: -2.31
  • ROTB: 1

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AXL,BRAF,CAMK2D,CDK5,CDK9,EIF2AK3,ERBB2,GRK2,ITK,MAP3K21,MAPK7,NTRK2,PDK2,PDK4,PIK3CB,PIK3CG,PRKDC 19
kinase-selectivity-class AXL,GRK2,PDK4 3
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Weight loss indication 89362005




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.19 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D02909 KEGG_DRUG
C0002589 UMLSCUI
CHEBI:134792 CHEBI
CHEMBL106258 ChEMBL_ID
DB01490 DRUGBANK_ID
D000635 MESH_DESCRIPTOR_UI
16630 PUBCHEM_CID
1652 INN_ID
2SH16612I9 UNII

Pharmaceutical products:

None