meprednisone Indications/Contra | FAERs | Orange Book | BioActivity |

Stem definitionDrug idCAS RN
prednisone and prednisolone derivatives 1702 1247-42-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • meprednisone
  • betalone
  • betanisona
  • bitanisone
  • methylprednisone
  • Molecular weight: 372.46
  • Formula: C22H28O5
  • CLOGP: 2.18
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 2
  • TPSA: 91.67
  • ALOGS: -3.72
  • ROTB: 2

Drug dosage:

None

Approvals:

DateAgencyCompanyOrphan
Jan. 26, 1978 FDA SCHERING

FDA Adverse Event Reporting System

None

Pharmacologic Action:

SourceCodeDescription
ATC H02AB15 SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
CORTICOSTEROIDS FOR SYSTEMIC USE
CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
Glucocorticoids

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.47 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Glucocorticoid receptor Nuclear hormone receptor AGONIST CHEMBL CHEMBL

External reference:

IDSource
C0065967 UMLSCUI
D06673 KEGG_DRUG
67U96J8P35 UNII
1967 INN_ID
29523 RXNORM
116603004 SNOMEDCT_US
61181002 SNOMEDCT_US
002178 NDDF
5284587 PUBCHEM_CID
CHEMBL1201148 ChEMBL_ID
C008352 MESH_SUPPLEMENTAL_RECORD_UI
DB12952 DRUGBANK_ID
CHEBI:135573 CHEBI

Pharmaceutical products:

None