mepixanox 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antiallergics, tixanox group 1701 17854-59-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • mepixanox
  • mepixanthone
  • pimexone
respiratory analeptic; RN given refers to parent cpd; & in Negwer, 5th ed, #6503
  • Molecular weight: 323.39
  • Formula: C20H21NO3
  • CLOGP: 4.11
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 0
  • TPSA: 38.77
  • ALOGS: -3.61
  • ROTB: 3

Drug dosage:

None

ADMET properties:

PropertyValueReference
BA (Bioavailability) 65 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R07AB09 RESPIRATORY SYSTEM
OTHER RESPIRATORY SYSTEM PRODUCTS
OTHER RESPIRATORY SYSTEM PRODUCTS
Respiratory stimulants

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.0 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07410 KEGG_DRUG
C0071070 UMLSCUI
CHEBI:135373 CHEBI
CHEMBL2104462 ChEMBL_ID
DB13579 DRUGBANK_ID
65687 PUBCHEM_CID
C033221 MESH_SUPPLEMENTAL_RECORD_UI
5296 INN_ID
7419T4YQQW UNII

Pharmaceutical products:

None