niclofolan 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
nicotinic acid or nicotinoyl alcohol derivatives 1686 10331-57-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • menichlopholan
  • menichlofolan
  • niclofolan
  • bilevon
Proposed fasciolacide. Synonyms: Dertil; Bilevon; Bay 9015.
  • Molecular weight: 345.09
  • Formula: C12H6Cl2N2O6
  • CLOGP: 4.50
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 2
  • TPSA: 132.10
  • ALOGS: -4.54
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.09 acidic
pKa2 6.63 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C0028016 UMLSCUI
CHEBI:135460 CHEBI
CHEMBL2107116 ChEMBL_ID
D009533 MESH_DESCRIPTOR_UI
2566 INN_ID
82KFT81F6W UNII
5284586 PUBCHEM_CID

Pharmaceutical products:

None