5-aminolevulinic acid hexyl ester indications/contra

Stem definitionDrug idCAS RN
167 140898-97-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • hexaminolevulinate
  • 5-aminolevulinic acid hexyl ester
  • aminolevulinic acid hexyl ester
  • Hexyl 5-amino-4-oxopentanoate
  • Hexyl 5-aminolevulinate
  • hexaminolevulinate hydrochloride
  • Molecular weight: 215.29
  • Formula: C11H21NO3
  • CLOGP: 1.97
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 1
  • TPSA: 69.39
  • ALOGS: -2.62
  • ROTB: 10

Drug dosage:

None

Approvals:

DateAgencyCompanyOrphan
May 28, 2010 FDA PHOTOCURE ASA

FDA Adverse Event Reporting System

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.43 Basic

Orange Book patent data (new drug applications)

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Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
100MG/VIAL CYSVIEW KIT PHOTOCURE ASA N022555 May 28, 2010 RX FOR SOLUTION INTRAVESICAL 7348361 Nov. 6, 2020 DETECTION OF NON-MUSCLE INVASIVE PAPILLARY CANCER OF THE BLADDER BY PHOTODYNAMIC CYSTOSCOPY

Orange Book exclusivity data (new drug applications)

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Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRouteExclusivity dateDescription
100MG/VIAL CYSVIEW KIT PHOTOCURE ASA N022555 May 28, 2010 RX FOR SOLUTION INTRAVESICAL Feb. 15, 2021 ADDITIONAL INFORMATION ADDED TO THE LABELING FROM STUDY PC B308/13 REGARDING THE USE OF BLUE LIGHT CYSTOSCOPY WITH CYSVIEW AS AN ADJUNCT TO WHITE LIGHT CYSTOSCOPY

Bioactivity Summary:

None

External reference:

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IDSource
4030912 VUID
N0000182977 NUI
C1327841 UMLSCUI
D04436 KEGG_DRUG
6433083 PUBCHEM_CID
4030912 VANDF
N0000182977 NDFRT
1426872 RXNORM
d06771 MMSL
012185 NDDF
CHEBI:134892 CHEBI
CHEMBL1201784 ChEMBL_ID
CHEMBL1201785 ChEMBL_ID
C419924 MESH_SUPPLEMENTAL_RECORD_UI
D4F329SL1O UNII
140898-91-5 SECONDARY_CAS_RN
DB06261 DRUGBANK_ID

Pharmaceutical products:

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ProductCategoryIngredientsNDCFormQuantityRoute MarketingLabel
Cysview HUMAN PRESCRIPTION DRUG LABEL 1 10511-3001 KIT 100 mg None NDA 17 sections