medifoxamine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1656 32359-34-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • medifoxamine
  • Molecular weight: 257.33
  • Formula: C16H19NO2
  • CLOGP: 3.38
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 0
  • TPSA: 21.70
  • ALOGS: -2.90
  • ROTB: 6

Drug dosage:

None

ADMET properties:

PropertyValueReference
BA (Bioavailability) 21 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H
Vd (Volume of distribution) 2.80 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 13.70 mL/min/kg Lombardo F, Berellini G, Obach RS
t_half (Half-life) 4.40 hours Lombardo F, Berellini G, Obach RS

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N06AX13 NERVOUS SYSTEM
PSYCHOANALEPTICS
ANTIDEPRESSANTS
Other antidepressants

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.35 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07341 KEGG_DRUG
C0065858 UMLSCUI
CHEMBL85231 ChEMBL_ID
DB13219 DRUGBANK_ID
C034065 MESH_SUPPLEMENTAL_RECORD_UI
36109 PUBCHEM_CID
3759 INN_ID
KWU7C2A1NT UNII
29434 RXNORM
005661 NDDF

Pharmaceutical products:

None