ketanserin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
serotonin receptor antagonists (mostly 5-HT2) 1524 74050-98-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • R 41 468
  • ketanserin
  • ketensin
  • suffrexal
  • ketanserin tartrate hydrate
  • ketanserin tartrate
  • R 41468
A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
  • Molecular weight: 395.43
  • Formula: C22H22FN3O3
  • CLOGP: 2.92
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 1
  • TPSA: 69.72
  • ALOGS: -3.40
  • ROTB: 5

Drug dosage:

DoseUnitRoute
40 mg O
40 mg P

ADMET properties:

Approvals:

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

None

ketanserin