isocarboxazid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1490 59-63-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • marplan
  • Ro 5-0831/1
  • Ro 5-0831
  • isocarboxazid
  • benazide
  • isocarboxazide
  • isocarboxyzid
An MAO inhibitor that is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in the treatment of panic disorder and the phobic disorders. (From AMA, Drug Evaluations Annual, 1994, p311)
  • Molecular weight: 231.26
  • Formula: C12H13N3O2
  • CLOGP: 0.99
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 2
  • TPSA: 67.16
  • ALOGS: -3.01
  • ROTB: 4

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

DoseUnitRoute
15 mg O

ADMET properties:

Approvals:

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

isocarboxazid