ioxaglic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
iodine-containing contrast media 1472 59017-64-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ioxaglic acid
  • Hexabrix 160
  • ioxaglate sodium
  • ioxaglate meglumine
  • ioxaglate
A low-osmolar, ionic contrast medium used in various radiographic procedures.
  • Molecular weight: 1268.89
  • Formula: C24H21I6N5O8
  • CLOGP: -0.76
  • LIPINSKI: 3
  • HAC: 13
  • HDO: 6
  • TPSA: 194.24
  • ALOGS: -4.92
  • ROTB: 10

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
July 26, 1985 FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V08AB03 VARIOUS
CONTRAST MEDIA
X-RAY CONTRAST MEDIA, IODINATED
Watersoluble, nephrotropic, low osmolar X-ray contrast media
FDA MoA N0000010258 X-Ray Contrast Activity
MeSH PA D003287 Contrast Media
MeSH PA D064907 Diagnostic Uses of Chemicals
FDA EPC N0000180185 Radiographic Contrast Agent
CHEBI has role CHEBI:37338 contrast media

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.22 acidic
pKa2 10.47 acidic
pKa3 11.47 acidic
pKa4 13.71 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000007294 NUI
D01761 KEGG_DRUG
67992-58-9 SECONDARY_CAS_RN
59018-13-2 SECONDARY_CAS_RN
4018193 VANDF
4018194 VANDF
4019789 VANDF
C0022041 UMLSCUI
CHEBI:31718 CHEBI
CHEMBL1201291 ChEMBL_ID
D007485 MESH_DESCRIPTOR_UI
DB09313 DRUGBANK_ID
4217 INN_ID
Z40X7EI2AF UNII
3742 PUBCHEM_CID
1426458 RXNORM
4910 MMSL
4911 MMSL
d03675 MMSL
000674 NDDF
000675 NDDF
003615 NDDF
353924001 SNOMEDCT_US
395760005 SNOMEDCT_US
CHEMBL1200743 ChEMBL_ID
CHEMBL1200508 ChEMBL_ID

Pharmaceutical products:

None