iopanoic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
iodine-containing contrast media 1465 96-83-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • iopanoic acid
  • iopanoicum
  • iodopanoic acid
  • iodopanic acid
Radiopaque medium used as diagnostic aid.
  • Molecular weight: 570.94
  • Formula: C11H12I3NO2
  • CLOGP: 4.70
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 2
  • TPSA: 63.32
  • ALOGS: -4.62
  • ROTB: 4

  • Status: OFM

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

PropertyValueReference
BDDCS (Biopharmaceutical Drug Disposition Classification System) 4 Benet LZ, Broccatelli F, Oprea TI
S (Water solubility) 0.02 mg/mL Benet LZ, Broccatelli F, Oprea TI
EoM (Fraction excreted unchanged in urine) 33 % Benet LZ, Broccatelli F, Oprea TI

Approvals:

DateAgencyCompanyOrphan
July 16, 1951 FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V08AC06 VARIOUS
CONTRAST MEDIA
X-RAY CONTRAST MEDIA, IODINATED
Watersoluble, hepatotropic X-ray contrast media
MeSH PA D003287 Contrast Media
MeSH PA D064907 Diagnostic Uses of Chemicals

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Diagnostic aid indication 2949005
Acute nephropathy contraindication 58574008
Hepatic failure contraindication 59927004
Kidney disease contraindication 90708001 DOID:557
Hb SS disease contraindication 127040003 DOID:10923
Asthma contraindication 195967001 DOID:2841
Pregnancy, function contraindication 289908002
Pheochromocytoma contraindication 302835009
Hypertensive Emergencies contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.84 acidic
pKa2 2.32 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4018259 VUID
N0000146589 NUI
D01014 KEGG_DRUG
4018259 VANDF
C0022028 UMLSCUI
CHEBI:5951 CHEBI
CHEMBL867 ChEMBL_ID
D007480 MESH_DESCRIPTOR_UI
DB08946 DRUGBANK_ID
3 INN_ID
FE9794P71J UNII
3735 PUBCHEM_CID
5967 RXNORM
4906 MMSL
d01438 MMSL
001220 NDDF
412227008 SNOMEDCT_US
76155001 SNOMEDCT_US

Pharmaceutical products:

None