iobitridol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| iodine-containing contrast media | 1449 | 136949-58-1 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
a nonionic monomeric low-osmolality contrast medium; structure given in second source
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Drug reaction with eosinophilia and systemic symptoms | 170.97 | 95.90 | 43 | 295 | 32969 | 34923624 |
| Toxic skin eruption | 100.77 | 95.90 | 23 | 315 | 11362 | 34945231 |
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Drug reaction with eosinophilia and systemic symptoms | 269.46 | 90.11 | 70 | 651 | 64174 | 79679493 |
| Acute kidney injury | 195.06 | 90.11 | 93 | 628 | 519311 | 79224356 |
| Rash maculo-papular | 163.34 | 90.11 | 46 | 675 | 56032 | 79687635 |
| Eosinophilia | 121.90 | 90.11 | 35 | 686 | 45310 | 79698357 |
| Toxic skin eruption | 115.89 | 90.11 | 29 | 692 | 22264 | 79721403 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | V08AB11 | VARIOUS CONTRAST MEDIA X-RAY CONTRAST MEDIA, IODINATED Watersoluble, nephrotropic, low osmolar X-ray contrast media |
| MeSH PA | D003287 | Contrast Media |
| MeSH PA | D064907 | Diagnostic Uses of Chemicals |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 13.71 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D01181 | KEGG_DRUG |
| C0296806 | UMLSCUI |
| CHEMBL2107212 | ChEMBL_ID |
| DB12407 | DRUGBANK_ID |
| C093233 | MESH_SUPPLEMENTAL_RECORD_UI |
| 7040 | INN_ID |
| 182ECH14UH | UNII |
| 65985 | PUBCHEM_CID |
| 87639 | RXNORM |
| 005259 | NDDF |
| 704384003 | SNOMEDCT_US |
| 715519002 | SNOMEDCT_US |
Pharmaceutical products:
None