Molfile
Inchi
Smiles
Synonyms:
-
iloprost
-
ciloprost
-
endoprost
-
ilomedin
-
ventavis
-
ZK36374
-
ZK-36374
-
ZK 36374
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An eicosanoid, derived from the cyclooxygenase pathway of arachidonic acid metabolism. It is a stable and synthetic analog of EPOPROSTENOL, but with a longer half-life than the parent compound. Its actions are similar to prostacyclin. Iloprost produces vasodilation and inhibits platelet aggregation.
- Molecular weight: 360.49
- Formula: C22H32O4
- CLOGP: 2.56
- LIPINSKI: 0
- HAC: 4
- HDO: 3
- TPSA: 77.76
- ALOGS: -4.62
- ROTB: 9
- Status: OFP
Legend: OFP - off patent OFM - off market ONP - on patent
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