alverine indications/contra

Stem definitionDrug idCAS RN
spasmolytics with a papaverine-like action 142 150-59-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • alverine hydrochloride
  • alverine
  • dipropylin
  • dipropyline
  • phenopropamine
  • phenpropamine
  • alverine citrate
  • alverine citrate salt
  • Molecular weight: 281.44
  • Formula: C20H27N
  • CLOGP: 5.50
  • LIPINSKI: 1
  • HAC: 1
  • HDO: 0
  • TPSA: 3.24
  • ALOGS: -5.47
  • ROTB: 9

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

scroll-->
SourceCodeDescription
ATC A03AX08 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
Other drugs for functional gastrointestinal disorders
ATC A03AX58 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
Other drugs for functional gastrointestinal disorders
CHEBI has role CHEBI:53784 antispasmodic drug
MeSH PA D001337 Autonomic Agents
MeSH PA D010276 Parasympatholytics
MeSH PA D018373 Peripheral Nervous System Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

scroll-->
Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.35 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

scroll-->
IDSource
C0051528 UMLSCUI
D02877 KEGG_DRUG
46TIR1560O UNII
95 INN_ID
3678 PUBCHEM_CID
418483003 SNOMEDCT_US
17627 RXNORM
349818006 SNOMEDCT_US
001763 NDDF
5982-87-6 SECONDARY_CAS_RN
CHEMBL253371 ChEMBL_ID
CHEBI:518413 CHEBI
CHEMBL1408594 ChEMBL_ID
DB01616 DRUGBANK_ID
C010846 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None