glycyrrhizic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1325 1405-86-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • glycyrrhizin
  • glycyrrhizic acid
  • 18beta-Glycyrrhizic acid
  • glycyrrhizinic acid
  • glycyron
  • glycyrrhetinic acid glycoside
  • glycyrrhizinate dipotassium
A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.
  • Molecular weight: 822.94
  • Formula: C42H62O16
  • CLOGP: 3.03
  • LIPINSKI: 3
  • HAC: 16
  • HDO: 8
  • TPSA: 267.04
  • ALOGS: -4.18
  • ROTB: 7

Drug dosage:

None

ADMET properties:

Approvals:

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

glycyrrhizic acid