almitrine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
127 27469-53-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • almitrine
  • almitrine mesylate
  • almitrine mesilate
  • duxil
  • almitrine dimesilate
  • almitrine dimesylate
A respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease. It may also prove useful in the treatment of nocturnal oxygen desaturation without impairing the quality of sleep.
  • Molecular weight: 477.56
  • Formula: C26H29F2N7
  • CLOGP: 6.59
  • LIPINSKI: 1
  • HAC: 7
  • HDO: 2
  • TPSA: 69.21
  • ALOGS: -4.52
  • ROTB: 10

Drug dosage:

DoseUnitRoute
0.10 g O

ADMET properties:

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

FDA Adverse Event Reporting System (Geriatric)

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

Pharmaceutical products:

None

almitrine