All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

furaltadone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definition	Drug id	CAS RN
5-nitrofuran derivatives	1256	139-91-3

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: furaltadone furmethanol furmethonol furmetonol medifuran furaltadon furantoina furazolin furazoline nitraldone nitrofurmethone nitrofurmeton furaltadone hydrochloride furaltadone HCl	Molecular weight: 324.29 Formula: C13H16N4O6 CLOGP: -0.12 LIPINSKI: 0 HAC: 10 HDO: 0 TPSA: 110.65 ALOGS: -2.77 ROTB: 5

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

Property	Description	Value	Unit	Confidence	Similarity
kinase-safety-class	ACVR2A,ACVR2B,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,GSK3B,ITK,JAK2,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPK9,MARK4,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CD,PIM2,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK	41
kinase-selectivity-class	AXL,BRAF,CAMK2D,CDK9,DDR1,DYRK1B,GRK2,GSK3B,IRAK1,MAP2K6,MAP3K21,MAPK7,MARK4,PRKDC,SIK2,STK33,SYK,TEK,TTK	19
pfas-class	PFAS structural alert (1 = True, 0 = False)	0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
MeSH PA	D000890	Anti-Infective Agents
MeSH PA	D000892	Anti-Infective Agents, Urinary
CHEBI has role	CHEBI:36047	antibacterial drug

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	5.83	Basic
pKa2	3.34	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Mitogen-activated protein kinase 9	Kinase	P45984	MK09_HUMAN		IC50	4.87		CHEMBL

External reference:

ID	Source
D02510	KEGG_DRUG
C0060849	UMLSCUI
CHEBI:74803	CHEBI
CHEMBL1189513	ChEMBL_ID
DB16567	DRUGBANK_ID
9553856	PUBCHEM_CID
13898	IUPHAR_LIGAND_ID
811	INN_ID
5X4V82ZN30	UNII
002856	NDDF
3759-92-0	SECONDARY_CAS_RN
C007795	MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None