All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

fudosteine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definition	Drug id	CAS RN
mucolytics	1254	13189-98-5

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: fudosteine cleanal	fudosteine is the (R)-isomer Molecular weight: 179.23 Formula: C6H13NO3S CLOGP: -2.42 LIPINSKI: 0 HAC: 4 HDO: 3 TPSA: 83.55 ALOGS: -0.73 ROTB: 6

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

Property	Description	Value	Unit	Confidence	Similarity
kinase-safety-class	ACVR2A,ACVR2B,ACVRL1,AKT3,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,GRK2,GSK3B,IGF1R,ITK,JAK1,JAK2,JAK3,KDR,MAP2K6,MAP3K14,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPK9,MAPKAPK2,MTOR,NTRK1,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ZAP70	55
kinase-selectivity-class	AXL,CDK9,CHUK,EPHB4,GRK2,MAP2K6,PIK3CD,TEK,TGFBR1	9
pfas-class	PFAS structural alert (1 = True, 0 = False)	0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Pneumonia	51.36	40.02	32	306	876682	109712279

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	2.08	acidic
pKa2	8.85	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
D01845	KEGG_DRUG
C0756016	UMLSCUI
CHEBI:31637	CHEBI
CHEMBL1555183	ChEMBL_ID
134669	PUBCHEM_CID
7613	INN_ID
C113797	MESH_SUPPLEMENTAL_RECORD_UI
UR9VPI71PT	UNII

Pharmaceutical products:

None