ftivazide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	1253	149-17-7

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

anhydrous ftivazide
ftivazide
ftivazid
N-Isonicotinamido-3-methoxy-4-hydroxybenzalimine
phthivazid
phthivazide
vanillaberon
vanizide

Molecular weight: 271.28
Formula: C14H13N3O3
CLOGP: 1.54
LIPINSKI: 0
HAC: 6
HDO: 2
TPSA: 83.81
ALOGS: -3.14
ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
MeSH PA	D000900	Anti-Bacterial Agents
MeSH PA	D000890	Anti-Infective Agents
MeSH PA	D000963	Antimetabolites
MeSH PA	D000995	Antitubercular Agents
MeSH PA	D054872	Fatty Acid Synthesis Inhibitors
MeSH PA	D000960	Hypolipidemic Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Tuberculosis	indication	56717001

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	8.51	acidic
pKa2	10.3	acidic
pKa3	4.53	Basic
pKa4	3.56	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Myeloperoxidase	Enzyme	P05164	PERM_HUMAN		IC50	6.34		CHEMBL

External reference:

ID	Source
C0086317	UMLSCUI
CHEBI:135117	CHEBI
CHEMBL2105120	ChEMBL_ID
135412163	PUBCHEM_CID
1087	INN_ID
40Q4C3O4V0	UNII
D007538	MESH_DESCRIPTOR_UI

Pharmaceutical products:

None