Molfile
Inchi
Smiles
Synonyms:
-
sodium ethacrynate
-
ethacrynic acid
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etacrynic acid
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ethacrynate
-
ethacrynate sodium
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A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
- Molecular weight: 303.14
- Formula: C13H12Cl2O4
- CLOGP: 3.29
- LIPINSKI: 0
- HAC: 4
- HDO: 1
- TPSA: 63.60
- ALOGS: -4.19
- ROTB: 6
- Status: OFP
Legend: OFP - off patent OFM - off market ONP - on patent
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