emepronium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
quaternary ammonium compounds 1000 27892-33-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • emepronium bromide
  • emepronium
  • emepronium carrageenate
A muscarinic antagonist used mainly in the treatment of urinary syndromes. It is incompletely absorbed from the gastrointestinal tract and does not cross the blood-brain barrier.
  • Molecular weight: 282.45
  • Formula: C20H28N
  • CLOGP: -0.50
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 0
  • TPSA:
  • ALOGS: -7.67
  • ROTB: 6

Drug dosage:

DoseUnitRoute
0.50 g O
75 mg P

ADMET properties:

PropertyValueReference
BDDCS (Biopharmaceutical Drug Disposition Classification System) 3 Hosey CM, Chan R, Benet LZ
BA (Bioavailability) 1 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H
S (Water solubility) 62.50 mg/mL Bocci G, Oprea TI, Benet LZ

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A03CA30 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
ANTISPASMODICS IN COMBINATION WITH PSYCHOLEPTICS
Synthetic anticholinergic agents in combination with psycholeptics
ATC G04BD01 GENITO URINARY SYSTEM AND SEX HORMONES
UROLOGICALS
UROLOGICALS
Drugs for urinary frequency and incontinence
ATC N05CX05 NERVOUS SYSTEM
PSYCHOLEPTICS
HYPNOTICS AND SEDATIVES
Hypnotics and sedatives in combination, excl. barbiturates
MeSH PA D018678 Cholinergic Agents
MeSH PA D018680 Cholinergic Antagonists
MeSH PA D018727 Muscarinic Antagonists
MeSH PA D018377 Neurotransmitter Agents
MeSH PA D010276 Parasympatholytics
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D064804 Urological Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07224 KEGG_DRUG
3614-30-0 SECONDARY_CAS_RN
CHEBI:135169 CHEBI
CHEMBL2110805 ChEMBL_ID
CHEMBL2106122 ChEMBL_ID
C046238 MESH_SUPPLEMENTAL_RECORD_UI
DB13505 DRUGBANK_ID
04QQ8SWA4U UNII
34055 PUBCHEM_CID
23944 RXNORM
005136 NDDF
005137 NDDF
005138 NDDF
398715005 SNOMEDCT_US
421158004 SNOMEDCT_US
421500009 SNOMEDCT_US
C0013954 UMLSCUI
D004629 MESH_DESCRIPTOR_UI
CHEMBL2109087 ChEMBL_ID
2414 INN_ID

Pharmaceutical products:

None